GIP (3-42), human HY-P2542 from MedChemExpress | Biocompare.com

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GIP (3-42), human

Description

GIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo

Product Specs
ItemGIP (3-42), human
CompanyMedChemExpress
Price $250.00Supplier Page View Company Product Page
Catalog NumberHY-P2542
Size1 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.75%
TypeChemical
Molecular Weight4749.4
FormulaC₂₁₄H₃₂₄N₅₈O₆₃S
Research AreaMetabolic Disease

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(1) Initial Exploration of the In Vitro Activation of GLP-1 and GIP Receptors and Pancreatic Islet Cell Protection by Salmon-Derived Bioactive PeptidesMarine DrugsOctober 30, 2024Crawford Currie, Christian Bjerknes, Bomi Framrozeantagonists for the GLP-1 and GIP receptors, Avexitide/Exenedin 9–39 (MCE HYP0264) and GIP 3–42 (MCE HYP2542), respectively. No antagonistic effects were observed at any of the tested SPH concentrations (0.1 mg/mL,

(2) GIP-(3-42) does not antagonize insulinotropic effects of GIP at physiological concentrationsAmerican journal of physiology. Endocrinology and metabolismSeptember 1, 2006Deacon CF, Plamboeck A, Rosenkilde MM, de Heer J, Holst JJ.

(3) Evidence that the major degradation product of glucose-dependent insulinotropic polypeptide, GIP(3-42), is a GIP receptor antagonist in vivoThe Journal of endocrinologyNovember 1, 2002Gault VA, Parker JC, Harriott P, Flatt PR, O'Harte FP.

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