GR 64349 HY-P1278 from MedChemExpress | Biocompare.com

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GR 64349

Description

GR 64349 is a potent and highly selective NK₂ receptor peptide antagonist, with an EC₅₀ of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK₁ and NK₃ receptors, respectively

Product Specs
ItemGR 64349
CompanyMedChemExpress
Price $320.00Supplier Page View Company Product Page
Catalog NumberHY-P1278
Size1 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
TypeChemical
Molecular Weight921.11
FormulaC₄₂H₆₈N₁₀O₁₁S
Research AreaNeurological Disease
Purity99.92%

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(1) Tachykinin receptor subtypes in the isolated guinea pig heart and their role in mediating responses to neurokinin AThe Journal of pharmacology and experimental therapeuticsJuly 1, 2000Chang Y, Hoover DB, Hancock JC, Smith FM.

(2) Conformationally constrained tachykinin analogues: potent and highly selective neurokinin NK-2 receptor agonistsJournal of medicinal chemistryOctober 30, 1992Deal MJ, Hagan RM, Ireland SJ, Jordan CC, McElroy AB, Porter B, Ross BC, Stephens-Smith M, Ward P.

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