Dkk-1 Protein, Mouse (CHO) HY-P7154 from MedChemExpress | Biocompare.com

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Dkk-1 Protein, Mouse (CHO)

Description

Dkk-1 Protein, Mouse (CHO) is shown to be a potent inhibitor of Wnt signaling and member of dickkopf family

Product Specs
ItemDkk-1 Protein, Mouse (CHO)
CompanyMedChemExpress
Price $620.00Supplier Page View Company Product Page
Catalog NumberHY-P7154
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
TypeProtein
Size50 µg
Molecular Weight19-20 kDa
Source/Expression SystemCHO
ActivityThe ED₅₀ is <6 µg/mL as measured in stimulation of alkaline phosphatase activity using CCl-226 cells
SpeciesMouse
NCBI Full Gene Namedickkopf WNT signaling pathway inhibitor 1
NCBI Gene Aliasesmdkk-1

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(1) DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathwayOncogeneNovember 4, 2004Niida A, Hiroko T, Kasai M, Furukawa Y, Nakamura Y, Suzuki Y, Sugano S, Akiyama T.

(2) Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouseDevelopmental cellSeptember 1, 2001Mukhopadhyay M, Shtrom S, Rodriguez-Esteban C, Chen L, Tsukui T, Gomer L, Dorward DW, Glinka A, Grinberg A, Huang SP, et al.

(3) Dickkopf-1 is a member of a new family of secreted proteins and functions in head inductionNatureJanuary 22, 1998Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C.

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