GsMTx4 TFA HY-P1410A from MedChemExpress

Product Specs
ItemGsMTx4 TFA
CompanyMedChemExpress
Price $270.00Supplier Page View Company Product Page
Catalog NumberHY-P1410A
Research AreaNeurological Disease; Inflammation/Immunology; Cardiovascular Disease
FormulaC₁₈₇H₂₇₄N₄₉F₃O₄₇S₆
Molecular Weight4209.85
TypeChemical
Purity99.85%
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Size500 µg

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(1) f-SPION-mediated magnetic stimulation induces reparative Schwann cell reprogramming via cytoskeletal dynamics - gated activation of Piezo1Journal of NanobiotechnologyFebruary 24, 2026Ting Liu, Mingxi Yang, Wantao Tian, Jingyan Ren, Laijin Lu, Yang WangGsMTx4 treatment group (designated “GsMTx4”): RSC96 cells were treated with 10 μM GsMTx4 (MCE, Cat. #HY-P1410A, Monmouth Junction, NJ, USA), a peptide inhibitor of Piezo family mechanosensitive ion channels, serving

(2) Engineered endoplasmic reticulum-targeting nanodrugs with Piezo1 inhibition and promotion of cell uptake for subarachnoid hemorrhage inflammation repairJ NanobiotechnologyApril 5, 2025Xiaojian Zhang, Enyan Jiang, Wangyang Fu, Yuanyuan Wang, Yiping Wang, Zhen Fang, Zichen Zhang, Jiajia Duan, Jia Zeng, Yang Yan, et al.therapies in other diseases. Experimental section Materials, cell culture, and animals GsMTx4 (HY-P1410A) was sourced from MCE (Guangzhou, China). Hemin solution (0.5 mg/mL, H8132) was provided by Solarbio

(3) Piezo1 promotes intervertebral disc degeneration through the Ca(2+)/F-actin/Yap signaling axisMolecular medicine (Cambridge, Mass.)March 8, 2025Peng F, Sun M, Jing X, Chen F, Cao T, Li Z, Li T.development of IVDD. Materials and methods Reagents Yoda1 (cat. no. HY-18723), GsMTx4 (cat. no. HY-P1410A) and Verteporfin (cat. no. HY-B0146) are purchased from MedChemExpress, Latrunculin A (cat. no. 10010630)

(4) Cell size regulates human endoderm specification through actomyosin-dependent AMOT-YAP signalingStem Cell ReportsAugust 13, 2024Lai Jiang, Chenchao Yan, Ying Yi, Lihang Zhu, Zheng Liu, Donghui Zhang, Wei Jiang2017; Akabayov et al., 2013). When indicated, 1 μM Yoda1 (Topscience, #T7506), 5 μM GsMTx-4 (MCE, #HY-P1410A), 1 μM PP1 (Topscience, #T6196), 1 μM PF-573228 (Topscience, #T2001), 10–100 nM jasplakinolide (Abcam,

(5) Run-and-Tumble Dynamics and Mechanotaxis Discovered in Microglial MigrationResearch (Wash D C)March 10, 2023Yiyu Zhang, Da Wei, Xiaochen Wang, Boyi Wang, Ming Li, Haiping Fang, Yi Peng, Qihui Fan, Fangfu Ye(0.87-μm diameter, Spherotech, FP-0856-2). The beads help track the gel deformation. GsMTx4 TFA (MCE, HY-P1410A) is used as the inhibitor of mechanosensing. It inhibits cation-permeable mechanosensitive and strain-activated

(6) Low-Intensity Pulsed Ultrasound Enhanced Adipose-Derived Stem Cell-Mediated Angiogenesis in the Treatment of Diabetic Erectile Dysfunction through the Piezo-ERK-VEGF AxisStem Cells InternationalJuly 29, 2022Shiyun Liu, Chenyi Jiang, Jianlin Hu, Huixing Chen, Bangmin Han, Shujie Xiagenes. 2.13. Western Blotting ADSCs were pretreated with PD98059 (HY-12028, 80 μM, MedChemExpress), GsMTx4 (HY-P1410A, 5 μM, MedChemExpress), and Yoda1 (HY-18723, 30 μM, MedChemExpress) for 1 hour as requested, and the

(7) Inhibition of Piezo1 attenuates demyelination in the central nervous systemGliaFebruary 1, 2020Velasco-Estevez M, Gadalla KKE, Liñan-Barba N, Cobb S, Dev KK, Sheridan GK.

(8) Adipokine Leptin Co-operates With Mechanosensitive Ca(2 +)-Channels and Triggers Actomyosin-Mediated Motility of Breast Epithelial CellsFrontiers in cell and developmental biologyJanuary 1, 2020Acheva A, Kärki T, Schaible N, Krishnan R, Tojkander S.

(9) Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cellsProceedings of the National Academy of Sciences of the United States of AmericaNovember 11, 2014Pathak MM, Nourse JL, Tran T, Hwe J, Arulmoli J, Le DT, Bernardis E, Flanagan LA, Tombola F.

(10) A tarantula spider toxin, GsMTx4, reduces mechanical and neuropathic painPainJuly 1, 2008Park SP, Kim BM, Koo JY, Cho H, Lee CH, Kim M, Na HS, Oh U.

(11) Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channelsThe Journal of general physiologyMay 1, 2000Suchyna TM, Johnson JH, Hamer K, Leykam JF, Gage DA, Clemo HF, Baumgarten CM, Sachs F.

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GsMTx4 TFA from MedChemExpress

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GsMTx4 TFA from MedChemExpress

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