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Prosaptide Tx14(A)
Prosaptide Tx14(A) from MedChemExpress
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Citations:
(5)
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Prosaptide Tx14(A)
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Description
Prosaptide Tx14(A), a prosaposin-derived peptide, is a potent
GPR37L1
and
GPR37
agonist with
EC
50
s of 5 and 7 nM, respectively. Prosaptide Tx14(A) increases both ERK1 and ERK2 phosphorylation in Schwann cells
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Prosaptide Tx14(A)
Company
MedChemExpress
Price
$160.00
Supplier Page
View Company Product Page
Catalog Number
HY-P1342
Research Area
Neurological Disease
Formula
C₆₉H₁₁₀N₁₆O₂₆
Molecular Weight
1579.7
Type
Chemical
Purity
99.51%
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Size
1 mg
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
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Website:
medchemexpress.com
Citations (5)
(1)
Prosaposin in CNS health and disease, metabolic stress and exercise adaptation
J Mol Med (Berl)
February 2, 2026
Hash Brown Taha, Shirley Zhu, Eric Wang
the dorsal root ganglia explant cultures,10 nM TX14(A),"Obtained commercially (
MedChemExpress
, Cat #
HY-P1342
)",1) TX14(A) increased ERK phosphorylation in some satellite glial cells2) TX14 upregulated
neurite
(2)
Genetically modified E. Coli secreting melanin (E.melanin) activates the astrocytic PSAP-GPR37L1 pathway and mitigates the pathogenesis of Parkinson's disease
Journal of nanobiotechnology
November 10, 2024
Kong W, Liu Y, Ai P, Bi Y, Wei C, Guo X, Cai Z, Gao G, Hu P, Zheng J,
et al
.
Atlas. A capsule within an osmotic pump containing 100 µL of
Prosaptide Tx14(A
) (3 µg; bs-0088R,
MCE
,
HY-P1342
) was affixed under the skin on the back. A plastic cannula was inserted into the ventricle and connected
(3)
Self-renewing macrophages in dorsal root ganglia contribute to promote nerve regeneration
Proceedings of the National Academy of Sciences of the United States of America
February 14, 2023
Feng R, Muraleedharan Saraswathy V, Mokalled MH, Cavalli V.
cell culture
slides (Celltreat, Catalog#229168) with 10 nM Prosaptide T×14(A) (
MedChemExpress
; Catalog#
HY-P1342
) or 0.1%DMSO in complete medium (
Neurobasal™-A Medium
, Thermofisher, Gibco; Catalog#
12349015
) with
(4)
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin
Proceedings of the National Academy of Sciences of the United States of America
June 4, 2013
Meyer RC, Giddens MM, Schaefer SA, Hall RA.
(5)
Prosaptide activates the MAPK pathway by a G-protein-dependent mechanism essential for enhanced sulfatide synthesis by Schwann cells
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
March 1, 1998
Campana WM, Hiraiwa M, O'Brien JS.
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Prosaptide Tx14(A) from MedChemExpress
Supplier Page
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$160.00
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