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S961 acetate
S961 acetate from MedChemExpress
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Citations:
(3)
Supplier Page
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MedChemExpress for
S961 acetate
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Description
S961 acetate is an high-affinity and selective
insulin receptor
(
IR
) antagonist with
IC
50
s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
S961 acetate
Company
MedChemExpress
Price
$300.00
Supplier Page
View Company Product Page
Catalog Number
HY-P2093B
Research Area
Metabolic Disease
Formula
C₂₁₃H₃₀₁N₅₅O₇₂S₂
Molecular Weight
4864.18
Type
Chemical
Purity
99.98%
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Size
5 mg
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (3)
(1)
hucMSC-derived exosomes targeting macrophage polarization attenuate systemic inflammation in T1DM via INS/SOD1 delivery
Stem Cell Res Ther
July 18, 2025
Xin Chen, Hong An, Yongbiao Du, Hao Zhong, Fangfang Zhang, Xiaomei Zeng, Fen Lv, Zhihua Tian, Zaixue Jiang, Qi Peng,
et al.
heat-inactivated hucMSC-EXOs (8.5 × 10^5 particles), LPS + hucMSC-EXOs + 5 nM
INS
receptor antagonist
S961
(
HY-P2093B
,
MCE
, US), and LPS + hucMSC-EXOs + 20 nM SOD1
inhibitor
ATN-224
(
HY-16074
,
MCE
, US).
ELISA
INS
(
CSB-E05069H
,
(2)
Upregulation of WDR6 drives hepatic de novo lipogenesis in insulin resistance in mice
Nature Metabolism
September 21, 2023
Zhenyu Yao, Ying Gong, Wenbin Chen, Shanshan Shao, Yongfeng Song, Honglin Guo, Qihang Li, Sijin Liu, Ximing Wang, Zhenhai Zhang,
et al.
2 or 12 h. To
inhibit
INSR activity, WDR6–FLAG cells were cultured with 10 nM
S961
(INSR
inhibitor
,
HY-P2093B
;
MedChemExpress
) for 4 h. To
knockdown
Insr, cells were
transfected
with siRNA targeting Insr for 48
(3)
A novel high-affinity peptide antagonist to the insulin receptor
Biochemical and biophysical research communications
November 14, 2008
Schäffer L, Brand CL, Hansen BF, Ribel U, Shaw AC, Slaaby R, Sturis J.
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S961 acetate from MedChemExpress
Supplier Page
View Company Product Page
$300.00
Product Specs
Company Info
Citations
Reviews
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