EME1 Recombinant Protein (Human) (OPCA02440) from Aviva Systems Biology

Description

Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks

Product Specs
ItemEME1 Recombinant Protein (Human) (OPCA02440)
CompanyAviva Systems Biology
Price Supplier Page View Company Product Page
Catalog NumberOPCA02440
Size25ul, 100ul
TypeProtein
Molecule NameCrossover junction endonuclease EME1
SpeciesHomo sapiens, Human
FormatIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0., Liquid or Lyophilized powder
PurityGreater than 90% as determined by SDS-PAGE
Gene Nameessential meiotic structure-specific endonuclease 1
Molecular Weight80.8 kDa
NCBI Gene AliasesMMS4L, SLX2A
Conjugate/TagN-terminal 6xHis-SUMO-tagged
Source/Expression SystemHuman

Sequence

MALKKSSPSL DSGDSDSEEL PTFAFLKKEP SSTKRRQPER EEKIVVVDIS DCEASCPPAP ELFSPPVPEI AETVTQTQPV RLLSSESEDE EEFIPLAQRL TCKFLTHKQL SPEDSSSPVK SVLDHQNNEG ASCDWKKPFP KIPEVPLHDT PERSAADNKD LILDPCCQLP AYLSTCPGQS SSLAVTKTNS DILPPQKKTK PSQKVQGRGS HGCRQQRQAR QKESTLRRQE RKNAALVTRM KAQRPEECLK HIIVVLDPVL LQMEGGGQLL GALQTMECRC VIEAQAVPCS VTWRRRAGPS EDREDWVEEP TVLVLLRAEA FVSMIDNGKQ GSLDSTMKGK ETLQGFVTDI TAKTAGKALS LVIVDQEKCF SLELLFFDFL PCTSAQNPPR RGKQGANKQT KKQQQRQPEA SIGSMVSRVD AEEALVDLQL HTEAQAQIVQ SWKELADFTC AFTKAVAEAP FKKLRDETTF SFCLESDWAG GVKVDLAGRG LALVWRRQIQ QLNRVSLEMA SAVVNAYPSP QLLVQAYQQC FSDKERQNLL ADIQVRRGEG VTSTSRRIGP ELSRRIYLQM TTLQPHLSLD SAD

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