BEND3 Recombinant Protein (Human) (OPCA03026) from Aviva Systems Biology

Description

Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909). Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites (By similarity). Stimulates the ERCC6L translocase and ATPase activities (PubMed:28977671)

Product Specs
ItemBEND3 Recombinant Protein (Human) (OPCA03026)
CompanyAviva Systems Biology
Price Supplier Page View Company Product Page
Catalog NumberOPCA03026
Size25ul, 100ul
TypeProtein
Molecule NameBEN domain-containing protein 3
SpeciesHomo sapiens, Human
FormatIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0., Liquid or Lyophilized powder
PurityGreater than 90% as determined by SDS-PAGE
Gene NameBEN domain containing 3
Molecular Weight17.5 kDa
NCBI Gene AliasesKIAA1553
Conjugate/TagN-terminal 6xHis-tagged
Source/Expression SystemHuman