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GSDMC Recombinant Protein (Human) (OPCA03311)
GSDMC Recombinant Protein (Human) (OPCA03311) from Aviva Systems Biology
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Citations:
(1)
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GSDMC Recombinant Protein (Human) (OPCA03311)
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Description
The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable)
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Product Specs
Item
GSDMC Recombinant Protein (Human) (OPCA03311)
Company
Aviva Systems Biology
Price
Supplier Page
View Company Product Page
Catalog Number
OPCA03311
Size
25ul, 100ul
Type
Protein
Format
Lyophilized
10mM Tris-HCl, 1mM EDTA, 6% Trehalose
Purity
Affinity purified using IMAC., Greater than 90% as determined by SDS-PAGE
Conjugate/Tag
N-terminal 6xHis-SUMO-tagged
Molecule Name
Gasdermin-C
Species
Homo sapiens, Human
Gene Name
gasdermin C
Molecular Weight
74 kDa
Source/Expression System
Human
NCBI Gene Aliases
MLZE
Sequence
Full Length:
MPSMLERISK NLVKEIGSKD LTPVKYLLSA TKLRQFVILR KKKDSRSSFW EQSDYVPVEF SLNDILEPSS SVLETVVTGP FHFSDIMIQK HKADMGVNVG IEVSVSGEAS VDHGCSLEFQ IVTIPSPNLE DFQKRKLLDP EPSFLKECRR RGDNLYVVTE AVELINNTVL YDSSSVNILG KIALWITYGK GQGQGESLRV KKKALTLQKG MVMAYKRKQL VIKEKAILIS DDDEQRTFQD EYEISEMVGY CAARSEGLLP SFHTISPTLF NASSNDMKLK PELFLTQQFL SGHLPKYEQV HILPVGRIEE PFWQNFKHLQ EEVFQKIKTL AQLSKDVQDV MFYSILAMLR DRGALQDLMN MLELDSSGHL DGPGGAILKK LQQDSNHAWF NPKDPILYLL EAIMVLSDFQ HDLLACSMEK RILLQQQELV RSILEPNFRY PWSIPFTLKP ELLAPLQSEG LAITYGLLEE CGLRMELDNP RSTWDVEAKM PLSALYGTLS LLQQLAEA
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Aviva Systems Biology
5754 Pacific Center Blvd
Suite 201
San Diego
,
California
92121
United States
Phone
: Toll Free: +1-888-880-0001
858-552-6979
Company Profile
Website:
http://www.avivasysbio.com/
Citations (1)
(1)
Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity
Immunity
October 14, 2025
Pandey SP, Yang D, Hedden L, Laughlin CR, Wang W, Soto AS, Winner H, Medina Sanchez L, Campana EE, Engl C,
et al
.
1183-CY-010
Recombinant Human GSDMC Protein (N-terminal 6xHis-SUMO-tagged),
Aviva Systems Biology
,Cat#
OPCA03311
"Recombinant Human GSDMC Protein (N-10xHis, C-Myc)",Byorbyt,Cat# orb595137_5
OC000459
(CRTH2
inhibitor
),
Cayman Chemical
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GSDMC Recombinant Protein (Human) (OPCA03311) from Aviva Systems Biology
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