ERP44 Recombinant Protein (Human) (OPCA04031) from Aviva Systems Biology

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ERP44 Recombinant Protein (Human) (OPCA04031)

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Description

Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum