ALKBH2 Recombinant Protein (Human) (OPCA04766) from Aviva Systems Biology

Description

Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron

Product Specs
ItemALKBH2 Recombinant Protein (Human) (OPCA04766)
CompanyAviva Systems Biology
Price Supplier Page View Company Product Page
Catalog NumberOPCA04766
Size25ul, 100ul
TypeProtein
Molecule NameDNA oxidative demethylase ALKBH2
SpeciesHomo sapiens, Human
FormatIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0., Liquid or Lyophilized powder
PurityGreater than 90% as determined by SDS-PAGE
Gene NamealkB homolog 2, alpha-ketoglutarate dependent dioxygenase
Molecular Weight56.3 kDa
NCBI Gene AliasesABH2
Conjugate/TagN-terminal GST-tagged
Source/Expression SystemE.coli

Sequence

MDRFLVKGAQ GGLLRKQEEQ EPTGEEPAVL GGDKESTRKR PRREAPGNGG HSAGPSWRHI RAEGLDCSYT VLFGKAEADE IFQELEKEVE YFTGALARVQ VFGKWHSVPR KQATYGDAGL TYTFSGLTLS PKPWIPVLER IRDHVSGVTG QTFNFVLINR YKDGCDHIGE HRDDERELAP GSPIASVSFG ACRDFVFRHK DSRGKSPSRR VAVVRLPLAH GSLLMMNHPT NTHWYHSLPV RKKVLAPRVN LTFRKILLTK K

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