DUSP26 Recombinant Protein (Human) (OPCA02463) from Aviva Systems Biology

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DUSP26 Recombinant Protein (Human) (OPCA02463)

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Description

Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK)