GFRAL Recombinant Protein (Human) (OPCA03451) from Aviva Systems Biology

Description

Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways

Product Specs
ItemGFRAL Recombinant Protein (Human) (OPCA03451)
CompanyAviva Systems Biology
Price Supplier Page View Company Product Page
Catalog NumberOPCA03451
Size25ul, 100ul
TypeProtein
Molecule NameGDNF family receptor alpha-like
SpeciesHomo sapiens, Human
FormatIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0., Liquid or Lyophilized powder
PurityAffinity purified using IMAC., Greater than 90% as determined by SDS-PAGE
ConcentrationVaries by lot. See vial for exact concentration
Gene NameGDNF family receptor alpha like
Molecular Weight53.8 kDa
NCBI Gene AliasesUNQ9356, bA360D14.1, GRAL, C6orf144
Conjugate/TagN-terminal 6xHis-SUMO-tagged
Source/Expression SystemE.coli

Sequence

SQTNNCTYLR EQCLRDANGC KHAWRVMEDA CNDSDPGDPC KMRNSSYCNL SIQYLVESNF QFKECLCTDD FYCTVNKLLG KKCINKSDNV KEDKFKWNLT TRSHHGFKGM WSCLEVAEAC VGDVVCNAQL ASYLKACSAN GNPCDLKQCQ AAIRFFYQNI PFNIAQMLAF CDCAQSDIPC QQSKEALHSK TCAVNMVPPP TCLSVIRSCQ NDELCRRHYR TFQSKCWQRV TRKCHEDENC ISTLSKQDLT CSGSDDCKAA YIDILGTVLQ VQCTCRTITQ SEESLCKIFQ HMLHRKSCFN YPTLSNVKGM ALYTRKHANK ITLTGFHSPF NGE

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