SSB Recombinant Protein (Human) (OPCA01872) from Aviva Systems Biology

Description

Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590). In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597)

Product Specs
ItemSSB Recombinant Protein (Human) (OPCA01872)
CompanyAviva Systems Biology
Price Supplier Page View Company Product Page
Catalog NumberOPCA01872
Size25ul, 100ul
TypeProtein
Molecule NameLupus La protein
SpeciesHomo sapiens, Human
FormatIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0., Liquid or Lyophilized powder
PurityAffinity purified using IMAC, Greater than 90% as determined by SDS-PAGE
ConcentrationVaries by lot. See vial for exact concentration
Gene Namesmall RNA binding exonuclease protection factor La
Molecular Weight62.8 kDa
NCBI Gene AliasesLa/SSB, LARP3, La
Conjugate/TagN-terminal 6xHis-SUMO-tagged
Source/Expression SystemHuman

Sequence

MAENGDNEKM AALEAKICHQ IEYYFGDFNL PRDKFLKEQI KLDEGWVPLE IMIKFNRLNR LTTDFNVIVE ALSKSKAELM EISEDKTKIR RSPSKPLPEV TDEYKNDVKN RSVYIKGFPT DATLDDIKEW LEDKGQVLNI QMRRTLHKAF KGSIFVVFDS IESAKKFVET PGQKYKETDL LILFKDDYFA KKNEERKQNK VEAKLRAKQE QEAKQKLEED AEMKSLEEKI GCLLKFSGDL DDQTCREDLH ILFSNHGEIK WIDFVRGAKE GIILFKEKAK EALGKAKDAN NGNLQLRNKE VTWEVLEGEV EKEALKKIIE DQQESLNKWK SKGRRFKGKG KGNKAAQPGS GKGKVQFQGK KTKFASDDEH DEHDENGATG PVKRAREETD KEEPASKQQK TENGAGDQ

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