FRK Recombinant Protein (OPCD03305) from Aviva Systems Biology

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FRK Recombinant Protein (OPCD03305)

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Description

Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor