ATXN1 Recombinant Protein (OPCD01549) from Aviva Systems Biology

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ATXN1 Recombinant Protein (OPCD01549)

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Description

Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (By similarity). May be involved in RNA metabolism (By similarity). In concert with CIC and ATXN1L, involved in brain development (PubMed:28288114)