GPR75 Recombinant Protein (Human) (OPCA02674) from Aviva Systems Biology

Description

G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor

Product Specs
ItemGPR75 Recombinant Protein (Human) (OPCA02674)
CompanyAviva Systems Biology
Price Supplier Page View Company Product Page
Catalog NumberOPCA02674
Size25ul, 100ul
TypeProtein
Molecule NameProbable G-protein coupled receptor 75
SpeciesHomo sapiens, Human
FormatIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0., Liquid or Lyophilized powder
PurityGreater than 90% as determined by SDS-PAGE
Gene NameG protein-coupled receptor 75
Molecular Weight20.9 kDa
NCBI Gene AliasesWI31133, GPRchr2
Conjugate/TagN-terminal 6xHis-tagged
Source/Expression SystemHuman

Sequence

NPFIYSRNSA GLRRKVLWCL QYIGLGFFCC KQKTRLRAMG KGNLEVNRNK SSHHETNSAY MLSPKPQKKF VDQACGPSHS KESMVSPKIS AGHQHCGQSS STPINTRIEP YYSIYNSSPS QEESSPCNLQ PVNSFGFANS YIAMHYHTTN DLVQEYDSTS AKQIPVPSV

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