DEDD Recombinant Protein (Human) (OPCA04872) from Aviva Systems Biology

Description

A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity)

Product Specs
ItemDEDD Recombinant Protein (Human) (OPCA04872)
CompanyAviva Systems Biology
Price Supplier Page View Company Product Page
Catalog NumberOPCA04872
Size25ul, 100ul
TypeProtein
Molecule NameDeath effector domain-containing protein
SpeciesHomo sapiens, Human
FormatIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0., Liquid or Lyophilized powder
PurityGreater than 90% as determined by SDS-PAGE
Gene Namedeath effector domain containing
Molecular Weight63.8 kDa
NCBI Gene AliasesCASP8IP1, FLDED-1, KE05, DEDPro1, DEFT, FLDED1, DEDD1
Conjugate/TagN-terminal GST-tagged
Source/Expression SystemE.coli

Sequence

MAGLKRRASQ VWPEEHGEQE HGLYSLHRMF DIVGTHLTHR DVRVLSFLFV DVIDDHERGL IRNGRDFLLA LERQGRCDES NFRQVLQLLR IITRHDLLPY VTLKRRRAVC PDLVDKYLEE TSIRYVTPRA LSDPEPRPPQ PSKTVPPHYP VVCCPTSGPQ MCSKRPARGR ATLGSQRKRR KSVTPDPKEK QTCDIRLRVR AEYCQHETAL QGNVFSNKQD PLERQFERFN QANTILKSRD LGSIICDIKF SELTYLDAFW RDYINGSLLE ALKGVFITDS LKQAVGHEAI KLLVNVDEED YELGRQKLLR NLMLQALP

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