RRM2B Recombinant Protein (Human) (OPCA04792) from Aviva Systems Biology

Description

Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage

Product Specs
ItemRRM2B Recombinant Protein (Human) (OPCA04792)
CompanyAviva Systems Biology
Price Supplier Page View Company Product Page
Catalog NumberOPCA04792
Size25ul, 100ul
TypeProtein
Molecule NameRibonucleoside-diphosphate reductase subunit M2 B
SpeciesHomo sapiens, Human
FormatIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0., Liquid or Lyophilized powder
PurityGreater than 90% as determined by SDS-PAGE
Gene Nameribonucleotide reductase regulatory TP53 inducible subunit M2B
Molecular Weight67.7 kDa
NCBI Gene AliasesMTDPS8A, MTDPS8B, P53R2, RCDFRD
Conjugate/TagN-terminal GST-tagged
Source/Expression SystemE.coli

Sequence

MGDPERPEAA GLDQDERSSS DTNESEIKSN EEPLLRKSSR RFVIFPIQYP DIWKMYKQAQ ASFWTAEEVD LSKDLPHWNK LKADEKYFIS HILAFFAASD GIVNENLVER FSQEVQVPEA RCFYGFQILI ENVHSEMYSL LIDTYIRDPK KREFLFNAIE TMPYVKKKAD WALRWIADRK STFGERVVAF AAVEGVFFSG SFAAIFWLKK RGLMPGLTFS NELISRDEGL HCDFACLMFQ YLVNKPSEER VREIIVDAVK IEQEFLTEAL PVGLIGMNCI LMKQYIEFVA DRLLVELGFS KVFQAENPFD FMENISLEGK TNFFEKRVSE YQRFAVMAET TDNVFTLDAD F

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