MBTPS1 Recombinant Protein (Human) (OPCA04328) from Aviva Systems Biology

Description

Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes

Product Specs
ItemMBTPS1 Recombinant Protein (Human) (OPCA04328)
CompanyAviva Systems Biology
Price Supplier Page View Company Product Page
Catalog NumberOPCA04328
Size25ul, 100ul
TypeProtein
Molecule NameMembrane-bound transcription factor site-1 protease
SpeciesHomo sapiens, Human
FormatIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0., Liquid or Lyophilized powder
PurityGreater than 90% as determined by SDS-PAGE
Gene Namemembrane bound transcription factor peptidase, site 1
Molecular Weight37.5 kDa
NCBI Gene AliasesPCSK8, S1P, SKI-1, SEDKF
Conjugate/TagN-terminal 6xHis-SUMO-tagged
Source/Expression SystemE.coli

Sequence

DTGLSEKHPH FKNVKERTNW TNERTLDDGL GHGTFVAGVI ASMRECQGFA PDAELHIFRV FTNNQVSYTS WFLDAFNYAI LKKIDVLNLS IGGPDFMDHP FVDKVWELTA NNVIMVSAIG NDGPLYGTLN NPADQMDVIG VGGIDFEDNI ARFSSRGMTT WELPGGYGRM KPDIVTYGAG VRGSGVKGGC RALSGTS

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