NKX2-2 Recombinant Protein (Mouse) (OPCA03134) from Aviva Systems Biology

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NKX2-2 Recombinant Protein (Mouse) (OPCA03134)

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Description

Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter