ORC4 Recombinant Protein (Human) (OPCA01771) from Aviva Systems Biology

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ORC4 Recombinant Protein (Human) (OPCA01771)

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Description

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3