Human BMP-4 Recombinant Protein PHC9531 from Thermo Fisher Scientific

Product Specs
ItemHuman BMP-4 Recombinant Protein
CompanyThermo Fisher Scientific
Price Supplier Page View Company Product Page
Catalog NumberPHC9531
Regulatory StatusFor Research Use Only. Not for use in diagnostic procedures
Size100 µg
ApplicationsCELL CULTURE

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Thermo Fisher Scientific

168 Third Avenue

Waltham, MA 02451

United States

Phone: 800-678-5599

Company Profile

Website: www.thermofisher.com

(1) Immune response to adeno-associated viral vectors in a human iPSC-derived microglia chimeric mouse modelCell Reports MethodsApril 20, 2026Jan R. Detrez, Caroline Eykens, Gaëlle Gillet, Manisha Padmakumar, Sílvia Cabré, Phil Stanley, Julien Gasser, Luke M. Healy, Irena KadiuFGF-Basic (AA 1–155) Recombinant Human Protein,ThermoFisher Scientific,PHG0266 BMP4 Recombinant Human Protein,ThermoFisher Scientific,PHC9534 Activin A Recombinant Human Protein,ThermoFisher Scientific,PHC9564 Recombinant Human VEGF 165,Peprotech,100–20 Thrombopoietin

(2) Targeting p75NTR activity alleviates the neurotoxic effect of high glucose on iPSC-derived dopaminergic neuronsStem Cell Research & TherapyMarch 21, 2026Konstantina Chanoumidou, Ioanna Zota, Maria Anna Papadopoulou, Chrystalla Konstantinou, Alexandros Tsimpolis, Electra Tsagliotis, Maria Tziortziou, Katerina Ntarntani, Anne Grünewald, Matthieu David Lavigne, et al.form EBs, in EB medium containing mTESR (Stem Cell Technologies, 100-0276), 50 ng/mL BMP4 (Invitrogen, PHC9534), 50 ng/mL VEGF (Invitrogen, PHC9394), and 20 ng/mL SCF (Miltenyi, 130-096-695) supplemented with 10

(3) Protocol to generate immunocompetent human heart-macrophage assembloids for the study of immune-cardiac interactionsSTAR ProtocMarch 20, 2026Colin O'Hern, Mia Dionise, Sammantha Caywood, Merlinda-Loraine Sewavi, Hussain Basrai, Priyadharshni Muniyandi, Brett Volmert, Aleksandra Kostina, Amanda Huang, Nagib Chalfoun, et al.#44-231-0 Recombinant Human Activin A,Fisher Scientific,Cat #338AC010 Recombinant Human BMP4,Fisher Scientific,Cat #PHC9534 Wnt-C59,Fisher Scientific,Cat #NC0710557 Recombinant Human SCF,R&D,Cat #255-SC-010 Recombinant Human

(4) Retinal organoid screening reveals ABT-737 and luminespib as potential agents against a cone- precursor-derived subtype of retinoblastomaMolecular Therapy OncologyMarch 19, 2026Joe Kelk, Agata Rozanska, Eleni Sotiriadou, Dan Astley, Rafiqul Hussain, Adrienne Unsworth, Abbie Gangar, Archie Robinson, Rachel Queen, Jonathan Coxhead, et al.out every 2 days. On day 6, the medium was supplemented with 1.5 mM Recombinant Human BMP-4 (Gibco PHC9534). At day 18, maintenance medium was introduced consisting of DMEM/F12 (Gibco 31330-038), 10% FBS (Gibco

(5) microRNA-132 attenuates inflammation in induced pluripotent stem cell-derived microglia from Alzheimer’s disease patientsActa Neuropathologica CommunicationsMarch 7, 2026Amber Penning, Sarah Snoeck, Olmo Ruiz Ormaechea, Dilara Ayyildiz, Oliver Polzer, Martin Buitrago-Arango, Raffaella Capobianco, Fred de Winter, Sriram Balusu, Joost Verhaagen, et al.by changing 75% of the medium with mTeSR1 containing 50 ng/mL Human BMP-4 Recombinant Protein (Cat#PHC9531, Thermo Fisher Scientific), 50 ng/mL Human VEGF-165 Recombinant Protein (Cat#100–20, Peprotech), and

(6) Effect of triazine thiols on steady-state mRNA levels in iPSC-derived hepatocytesMicroPubl BiolMarch 6, 2026Carla Martinez-Morant, Jui-Tung Liu, Yu-Lin Jiang, Josef Blaszkiewicz, Stephen A. Duncanng/mL Fibroblast Growth Factor 2 (FGF2) (Invitrogen, MA, #PHG0023), and 10 ng/mL BMP4 (Invitrogen, MA, #PHC9533). Over the next 3 days, the cells were induced to form definitive endoderm by culturing in B27 Supplement

(7) Protocol for inducing dorsal spinal sensory interneurons from mouse embryonic stem cell-derived neuromesodermal progenitorsSTAR ProtocolsMarch 1, 2026Cristian Rodriguez, Salena Gallardo, Sandeep Gupta, Samantha J. Butler,Thermo Fisher Scientific,PHG0023 Hydrochloric acid,Thermo Fisher Scientific,A144-212 Human BMP4 recombinant protein,Thermo Fisher Scientific,PHC9534 Matrigel Matrix,Corning,354277 Mouse LIF (mLIF),MilliporeSigma,ESG1107 N-2 Supplement (100x),Thermo Fisher Scientific

(8) Assessing Aβ-independent effects of Module 42 on immune function in vitroAlzheimers DementFebruary 25, 2026Ishita Ajith, Souvika Bakshi, Emma Mead, Opher Gileadi, Vittorio L. Katis, Paul E. Brennan, Emory‐Sage‐SGC‐Jax TREAT‐AD Center, Katerina O. GospodinovaSTEMCELL Technologies) and maintained in mTeSR™1 medium supplemented with (Bone morphogenetic protein‐4; 50 ng/mL, PHC9534, Life Technologies), (Vascular endothelial growth factor; 50 ng/mL, PHC9391, Life Technologies), and

(9) Nervous System-on-Chip: Innovative Microfluidic Platform to Compartmentalize hiPSC-Derived Neural NetworksMicromachines (Basel)February 1, 2026Rahman Sabahi-Kaviani, Antigoni Gogolou, Celine Souilhol, Mark van der Kroeg, Steven A. Kushner, Femke M. S. de Vrij, Anestis Tsakiridis, Regina LuttgeTocris, Bristol, UK, #1614), CHIR99021 (1 μM, Tocris, #4423), BMP4 (20 ng/mL, Thermo Fisher Scientific, #PHC9534), the BMP type-I receptor inhibitor DMH-1 (1 μM, Tocris, #4126), and ROCK inhibitor Y-27632 2HCl (10

(10) Conserved phenotype and function of human brain border-associated macrophages in iPSC-derived modelsbioRxivDecember 13, 2025Helena J. Barr, Constanze Depp, Maximilian Hingerl, Trang Nguyen, Justin M. Reimertz, Emma Connolly, Jasmin Patel, Jordan L. Doman, Samuel E. Marsh, Beth Stevens12.5ng/mL Activin-A (Thermo Fisher Scientific, cat #PHC9564), 50ng/mL BMP4 (Thermo Fisher Scientific, cat #PHC9534), 50ng/mL FGF2 (Thermo Fisher Scientific, cat #PHG0261), 2mM LiCL (Sigma, cat #L7026), and 1 μM ROCK

(11) Human heart-macrophage assembloids recapitulate immune-cardiac interactions and enable arrhythmia disease modelingCell Stem CellNovember 6, 2025Colin O’Hern, Sammantha Caywood, Shakhlo Aminova, Artem Kiselev, Brett Volmert, Weiheng Cao, Fei Wang, Mia Dionise, Merlinda-Loriane Sewavi, Milana Skoric, et al.#44-231-0 Recombinant Human Activin A,Fisher Scientific,Cat #338AC010 Recombinant Human BMP4,Fisher Scientific,Cat #PHC9534 Wnt-C59,Fisher Scientific,Cat #NC0710557 Recombinant Human SCF,R&D,Cat #255-SC-010 Recombinant Human

(12) A cross-study transcriptional patient map of heart failure defines conserved multicellular coordination in cardiac remodelingNature CommunicationsOctober 31, 2025Jan D. Lanzer, Ricardo O. Ramirez Flores, José Liñares Blanco, Marco Steier, Ashraf Y. Rangrez, Norbert Frey, Julio Saez-Rodrigueztreating them with either Bone morphogenetic protein 4 (BMP4, 10 ng/ml, Thermofisher with Catalog # PHC9531), Neuregulin 1 (NRG1, 10 ng/ml, MedChemExpress with Catalog # HY-P702533), Matrix remodeling associated

(13) APOA1 binding protein promotes lymphatic cell fate and lymphangiogenesis by relieving caveolae-mediated inhibition of VEGFR3 signalingNat CommunOctober 21, 2025Jun-Dae Kim, Surbhi Chaudhary, Weiqing Chen, Jonathan Astin, Philip S. Crosier, Pengchun Yu, John P. Cooke, Henry J. Pownall, Hugo J. Bellen, Nhat-Tu Le, et al.IV-coated plates and maintained in LEC differentiation medium supplemented with 2 ng/ml BMP4 (Cat #PHC9534, Gibco), 10 ng/ml bFGF (Cat #233-FB/CF, R&D systems), 50 ng/ml VEGFA (Cat #293, R&D systems), and 50

(14) Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer's disease through disrupted regulated intramembrane proteolysisMol NeurodegenerJune 20, 2025Oliver J. Ziff, Gustavo Morrone Parfitt, Sarah Jolly, Jackie M. Casey, Lucy Granat, Satinder Samra, Núria Setó-Salvia, Argyro Alatza, Leela Phadke, Benjamin Galet, et al.astrocytes, GPCs of at least 150 DIV were subjected to two weeks maturation with 10ng/ml BMP4 (Thermo PHC9534) and 10ng/ml LIF (Sigma, L5283) in N2B27 media. iPSC-microglia were generated using established protocols

(15) In vitro models of microglia: a comparative studySci RepMay 5, 2025Zoe Woolf, Taylor J. Stevenson, Kevin Lee, Blake Highet, Jena Macapagal Foliaki, Ramona Ratiu, Justin Rustenhoven, Jason Correia, Patrick Schweder, Peter Heppner, et al.ng/mL, Miltenyi, 130-096-692), VEGF165 (50 ng/mL, PeproTech, 100 − 20) and BMP4 (50 ng/mL, Invitrogen, PHC9534) before transferring embryoid bodies into two T175 flasks containing Advanced DMEM/F12 (Gibco, 12634010)

(16) Signaling Centers Drive Brachyury Dynamics and Lineage Commitment in mESC AggregatesFASEB BioAdvancesMay 2, 2025A. Rabeling, M. Goolampulse conditions, 80 μL of fresh N2B27 supplemented with either 3 μM Chiron or 1 ng/mL BMP4 (Gibco PHC9534) was added [42]. In all conditions, this was removed and replaced with further fresh medium at 72 h

(17) Mitochondrial dysfunction drives a neuronal exhaustion phenotype in methylmalonic aciduriaCommun BiolMarch 11, 2025Matthew C. S. Denley, Monique S. Straub, Giulio Marcionelli, Miriam A. Güra, David Penton, Igor Delvendahl, Martin Poms, Beata Vekeriotaite, Sarah Cherkaoui, Federica Conte, et al.followed, as reported below. For endoderm, 100 ng/mL Activin, 80 ng/mL FGF2, 10 ng/mL BMP-4 (Gibco, PHC9534), 10 μM LY294002 (Gibco, Cat. PHZ1144), and 3 μM CHIR99021 (Sigma, Cat. SML1046-5MG) were supplemented

(18) SOX9 haploinsufficiency reveals SOX9-Noggin interaction in BMP-SMAD signaling pathway in chondrogenesisCell Mol Life SciMarch 2, 2025Tin-Yan Ha, See-Wing Chan, Zhangting Wang, Patrick Wai Nok Law, Kai-Kei Miu, Gang Lu, Wai-Yee ChanRecombinant Human/Murine/Rat Activin A (PEPROTECH, 120-14P), bFGF (Thermo Scientific™, PHG6015), BMP4 (Invitrogen, PHC9533), Follistatin 300 human (Sigma, F1175-25UG), GDF-5 human (Sigma, SRP4667-50UG), and Recombinant Human NT-4 Protein

(19) Differentiation of mesenchymal stem cells towards lens epithelial stem cells based on three-dimensional bio-printed matrixFront Cell Dev BiolJanuary 6, 2025Yufan Liu, Zuowei Wang, Tianju Ma, Yi Gao, Wenqian Chen, Zi Ye, Zhaohui LiN2/B27-DMEM-FBS medium containing 100 ng/mL Noggin (PHC1506, Gibco, United States), 20 ng/mL BMP4 (PHC9534, Gibco, United States), 20 ng/mL BMP7 (PHC7204, Gibco, United States) and 100 ng/mL FGF-basic (FGF-2/bFGF,

(20) Netrin1 patterns the dorsal spinal cord through modulation of Bmp signalingCell ReportsNovember 26, 2024Sandy Alvarez, Sandeep Gupta, Yesica Mercado-Ayon, Kaitlyn Honeychurch, Cristian Rodriguez, Riki Kawaguchi, Samantha J. Butlerplates the day before stimulation with netrin1 (R&D, cat# 1109-N1–025) and Bmp4 (Thermo Fisher cat# PHC9534). On the day of stimulation, the cells were starved in FBS-free media for an hour prior to stimulation

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Human BMP-4 Recombinant Protein from Thermo Fisher Scientific

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Human BMP-4 Recombinant Protein from Thermo Fisher Scientific

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