Human CNTF Recombinant Protein PHC7015 from Thermo Fisher Scientific

Product Specs
ItemHuman CNTF Recombinant Protein
CompanyThermo Fisher Scientific
Price Supplier Page View Company Product Page
Catalog NumberPHC7015
Regulatory StatusFor Research Use Only. Not for use in diagnostic procedures
Size20 µg
ApplicationsCELL CULTURE

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Thermo Fisher Scientific

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Waltham, MA 02451

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Phone: 800-678-5599

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Website: www.thermofisher.com

(1) Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machineryJ NeuroinflammationApril 24, 2025Chiara Beretta, Abdulkhalek Dakhel, Khalid Eltom, Fredrik Rosqvist, Simon Uzoni, Tobias Mothes, John S. Fletcher, Ulf Risérus, Dag Sehlin, Jinar Rostami, et al.ng/ml (Sigma-Aldrich, SRP3069). From day 15, 20 ng/ml ciliary neurotrophic factor (CNTF; ThermoFisher, PHC7015) was also included. Culture medium was changed every other day until day 28. For experiments, fully

(2) The Influence of Pathological Extracellular Matrix on the Biological Properties of Stem Cells: Possible Hints for Cell Transplantation Therapies in Spinal Cord InjuryInternational Journal of Molecular SciencesApril 23, 2025Giuseppe Alastra, Corinne Quadalti, Vito Antonio Baldassarro, Alessandro Giuliani, Luciana Giardino, Laura Calzàmedium with the addition of 50 nM T3 (Sigma-Adlrich; cat no. T2752), 10 ng/mL CNTF (Gibco, cat no. PHC7015), 1× N-acetyl-L-cysteine—NAC (Thermo Fisher Scientific, cat no. A15409.36). Half medium was changed

(3) Non-muscle myosin II inhibition at the site of axon injury increases axon regenerationNature communicationsMarch 26, 2025Heo K, Ho TS, Zeng X, Turnes BL, Arab M, Jayakar S, Chen K, Kimourtzis G, Condro MC, Fazzari E, et al.10 ng/mL of recombinant human BDNF (#PHC7074, Thermo Fisher), GDNF (#450-10, PeproTech) and CNTF (#PHC7015, Thermo Fisher) were added prior to feeding. For growth permissive condition, 8000 cells per well were

(4) Astrocytic accumulation of tau fibrils isolated from Alzheimer's disease brains induces inflammation, cell-to-cell propagation and neuronal impairmentActa neuropathologica communicationsFebruary 26, 2024Eltom K, Mothes T, Libard S, Ingelsson M, Erlandsson A.120-14E) and 8 ng/ml bFGF (Thermo Fisher, 13,256,029). From day 15, 20 ng/ml of CNTF (Thermo Fisher, PHC7015) was also included. Culture medium was changed every other day until day 28. For experiments, fully

(5) Astrocytic uptake of neuronal corpses promotes cell-to-cell spreading of tau pathologyActa Neuropathologica CommunicationsJune 17, 2023Tobias Mothes, Benjamin Portal, Evangelos Konstantinidis, Khalid Eltom, Sylwia Libard, Linn Streubel-Gallasch, Martin Ingelsson, Jinar Rostami, Maria Lindskog, Anna Erlandssonng/ml IGF-1 (Sigma, SRP3069). From week three of differentiation, 20 ng/ml of CNTF (Thermo Fisher, PHC7015) was also included. A full medium change was performed every other day for the duration of the differentiation.

(6) Amyloid-β accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolismJournal of neuroinflammationFebruary 20, 2023Zyśk M, Beretta C, Naia L, Dakhel A, Påvénius L, Brismar H, Lindskog M, Ankarcrona M, Erlandsson A.ng/ml (Sigma-Aldrich, SRP3069). Additionally, 20 ng/ml ciliary neurotrophic factor (CNTF; ThermoFisher, PHC7015) was added to the medium for the last 2 weeks of culture. Cells were passaged using trypsin 0.05% EDTA

(7) Intracellular deposits of amyloid-beta influence the ability of human iPSC-derived astrocytes to support neuronal functionJournal of neuroinflammationJanuary 3, 2023Konstantinidis E, Portal B, Mothes T, Beretta C, Lindskog M, Erlandsson A.factor 1 (IGF-1) 200 ng/ml (#SRP3069, Merck) and human ciliary neurotropic factor (CNTF) 20 ng/ml (#PHC7015, Thermo Fisher Scientific). The medium was changed every other day and astrocytes were passaged using

(8) Bortezomib-induced neurotoxicity in human neurons is the consequence of nicotinamide adenine dinucleotide depletionDisease Models & MechanismsDecember 1, 2022Andrew R. Snavely, Keungjung Heo, Veselina Petrova, Tammy Szu-Yu Ho, Xuan Huang, Crystal Hermawan, Ruth Kagan, Tao Deng, Ilyas Singeç, Long Chen, et al.(Thermo Fisher Scientific, PHC7045) and 10 ng/ml recombinant human CNTF (Thermo Fisher Scientific, PHC7015)] on plates coated with poly-D-lysine and laminin at a density appropriate for the assay. Dissociated

(9) EphA4 targeting agents protect motor neurons from cell death induced by amyotrophic lateral sclerosis -astrocytesiScienceSeptember 16, 2022Dennys C, Baggio C, Rodrigo R, Roussel F, Kulinich A, Heintzman S, Fox A, Kolb SJ, Shaw PJ, Ethell IM, et al."DMEM, High Glucose",Gibco,10569010 F12 (ham),ThermoFisher,11765–062 BDNF,ThermoFisher,PHC7074 CDNF,ThermoFisher,PHC7015 GDNF,ThermoFisher,PHC7041 SAG,Sigma,56660-1MG Retinoic Acid,Sigma,R2625 LIF (human),Millipore,ESG1106 Fibronectin,Millipore,FC010-10MG Mouse

(10) Genome-wide identification of the genetic basis of amyotrophic lateral sclerosisNeuronMarch 16, 2022Zhang S, Cooper-Knock J, Weimer AK, Shi M, Moll T, Marshall JNG, Harvey C, Nezhad HG, Franklin J, Souza CDS, et al.acid,Sigma,#R2625 BDNF,PeproTech,#450-02 IGF,ThermoFisher Scientific,#PHG0078 CNTF,ThermoFisher Scientific,#PHC7015 N-2 supplement,ThermoFisher Scientific,#17502048 B-27 supplement,ThermoFisher Scientific,#17504001 DMH-1,Tocris Bioscience

(11) Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validationCell reportsJune 8, 2021Huang X, Roet KCD, Zhang L, Brault A, Berg AP, Jefferson AB, Klug-McLeod J, Leach KL, Vincent F, Yang H, et al.Human GDNF recombinant protein,Thermo Fisher,Cat# PHC7045 Human CNTF recombinant protein,Thermo Fisher,Cat# PHC7015 EdU,Thermo Fisher,Cat# A10044 Critical commercial assays,Critical commercial assays,Critical commercial

(12) Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregatesJournal of neuroinflammationJune 3, 2021Rostami J, Mothes T, Kolahdouzan M, Eriksson O, Moslem M, Bergström J, Ingelsson M, O'Callaghan P, Healy LM, Falk A, et al.ng/ml (Sigma Aldrich, SRP3069). Additionally, 20 ng/ml ciliary neurotropic factor (CNTF; Thermo Fisher, PHC7015) was added to the medium the last 2 weeks of differentiation. Cells were seeded for experiment, at a

(13) Establishing Human Male and Female Models of Cholinergic Neurons via Neurokine-Mediated Differentiation of LA-N-2 and LA-N-5 Neuroblastoma CellsSTAR ProtocolsDecember 30, 2020Sebastian Lobentanzer, Jochen Klein, Hermona SoreqProteins","Chemicals, Peptides, and Recombinant Proteins" ,, "CNTF, human, recombinant",Thermo Fisher Scientific,PHC7015 "Glycogen, RNA-grade",Thermo Fisher Scientific,R0551 Phenol/guanidinium thiocyanate solution (TRIzol),Thermo Fisher Scientific

(14) Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor NeuronsScientific reportsJuly 25, 2019Moakley D, Koh J, Pereira JD, DuBreuil DM, Devlin AC, Berezovski E, Zhu K, Wainger BJ.Life Technologies, PHC7044), BDNF (10 ng/ml, Life Technologies, PHC7074), and CNTF (10 ng/ml, Life Technologies, PHC7015) with half media changes 3 times per week. Primary mouse motor neuron dissection and maintenance Embryonic

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Human CNTF Recombinant Protein from Thermo Fisher Scientific

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Human CNTF Recombinant Protein from Thermo Fisher Scientific

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