Human IGF-I Recombinant Protein PHG0071 from Thermo Fisher Scientific

Product Specs
ItemHuman IGF-I Recombinant Protein
CompanyThermo Fisher Scientific
Price Supplier Page View Company Product Page
Catalog NumberPHG0071
Regulatory StatusFor Research Use Only. Not for use in diagnostic procedures
Size100 µg
ApplicationsCELL CULTURE

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Thermo Fisher Scientific

168 Third Avenue

Waltham, MA 02451

United States

Phone: 800-678-5599

Company Profile

Website: www.thermofisher.com

(1) STAT-independent functions of Janus kinases 1 and 2 are obligatory for the postnatal development of mammary epithelial ductsCell ReportsJanuary 27, 2026Rayane Dennaoui, Madison N. Wicker, Carson Moen, Michaela Schlederer, Kerry Vistisen, Aleata A. Triplett, Thomas Rülicke, Hallgeir Rui, Lukas Kenner, Emilio Casanova, et al.Cat. #12405), 10 ng/mL IFN-γ (Millipore, IF005), and 100 nM human recombinant IGF-I (Invitrogen, Cat. #PHG0071). Cells were harvested, flash-frozen on dry ice, and stored at − 80°C before being used in immunoblotting

(2) Phosphoproteomics unveils the signaling dynamics in neuronal cells stimulated with insulin and insulin-like growth factorsCell Communication and SignalingDecember 11, 2025Mereena George Ushakumary, Ryan L. Sontag, Camilo Posso, Thomas L. Fillmore, Maisie E. Topping, Heather M. Olson, Philip L. De Jager, David A. Bennett, Zoe Arvanitakis, Vladislav A. Petyuk(Thermo Fisher Scientific, Cat # 12585-014), recombinant human IGF-1 (Thermo Fisher Scientific, Cat # PHG0071), and recombinant human IGF-2 (Thermo Fisher Scientific, Cat # PHG0084). Cell lysates were collected

(3) Mitochondrial structure and function in OCRL depleted cellsFrontiers in Cell and Developmental BiologyNovember 20, 2025Ron George Philip, Priyanka Bhatia, Yojet Sharma, Padinjat Raghumedium (NDM) supplemented with 10 ng/mL BDNF (Gibco # PHC7074), GDNF (Gibco #PHC7041), IGF (Gibco, #PHG0078) ascorbic acid (50 μM, Sigma # A4544), and dbcAMP (1000μM, Sigma #D0627). During the first 14 days after

(4) Curcumin inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells via IGF-1/PI3K/Akt pathwayJ Int Med ResFebruary 8, 2025Chao Chen, Qiwu Wang, Jiwen Liu(D2650, Sigma-Aldrich). Human recombinant IGF-I protein was purchased from Thermo Fisher Scientific (PHG0078, Gibco). The primary antibodies used included anti-β-actin rabbit monoclonal antibody (mAb) (4970, Cell Signaling Technology

(5) Blood-brain barrier permeability increases with the differentiation of glioblastoma cells in vitroFluids and barriers of the CNSNovember 1, 2024Digiovanni S, Lorenzati M, Bianciotto OT, Godel M, Fontana S, Akman M, Costamagna C, Couraud PO, Buffo A, Kopecka J, et al.2-mercaptoethanol, 1% N2 supplement, 2% B27 (#17504044), 10 ng/mL PDGFa (#PHG0035), 10 ng/mL IGF-1 (#PHG0078), 5 ng/mL HGF (#PHG0254), 10 ng/mL NT3 (#PHC7036; all from Thermofisher Scientific), and 1% rh-insulin

(6) Skeletal overgrowth in a pre-pubescent child treated with pan-FGFR inhibitorHeliyonJune 15, 2024Majlessipour F, Zhu G, Baca N, Kumbaji M, Hwa V, Danielpour M.for 30 min, prior to the addition of FGF2 (R&D Systems, Cat No. 233-FB-01 M), IGF-I (Gibco, Cat No. PHG0078), or IGF2 (R&D Systems, Cat No. 292-G2-050), in co-treatment experiments. The 5 mM erdafitinib concentrated

(7) Evaluation of Lipids and Lipid-Related Transcripts in Human and Ovine Theca Cells and an in Vitro Mouse Model Exposed to the Obesogen Chemical TributyltinEnvironmental Health PerspectivesApril 17, 2024Natalia Pascuali, Yong Pu, Anita A. Waye, Sarah Pearl, Denny Martin, Allison Sutton, Ariella Shikanov, Almudena Veiga-Lopezmedium) or luteinizing (growth medium supplemented with 250 ng/mL ovine LH and 50 ng/mL (IGF-I; Cat. no. PHG0071; Invitrogen) stages. To evaluate whether other congeners in the organotin family could impact theca cell

(8) Retinal Progenitor Cells Exhibit Cadherin-Dependent Chemotaxis across Transplantable Extracellular Matrix of In Vitro Developmental and Adult ModelsJournal of Tissue Engineering and Regenerative MedicineAugust 24, 2023Miles W. Markey, Caroline D. Pena, Tadmiri Venkatesh, Li Cai, Maribel VazquezThermoFisher Catalog #PHG0311),20 ng/mL,MPs Insulin-like growth factor 1 (IGF1; ThermoFisher Catalog #PHG0071),50 ng/mL,MPs Fibroblast growth factor-8 (FGF-8; ThermoFisher Catalog #RP-87808),10 ng/mL,MPs Pyramus

(9) Single-molecule tracking of myelin basic protein during oligodendrocyte differentiationBiological ImagingApril 1, 2023Sayed M. Rassul, Masahiro Otsu, Iain B. Styles, Robert K. Neely, Daniel FultonThermofisher), 2 nM l-Glutamine, 1% Pen Strep, 20 ng/ml rhFGF2 (PHG0266, Thermofisher), 100 ng/ml IGF1 (PHG0078, Thermofisher), 20 ng/ml PDGF-AA (PHG0035, Thermofisher), 3.6 ng/ml Hydrocortisone (H0888, Sigma), and

(10) An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cellsSTAR protocolsDecember 16, 2022Surendran H, Soundararajan L, Reddy K VB, Subramani J, Stoddard J, Reynaga R, Tschetter W, Ryals RC, Pal R.μM),Sigma-Aldrich,H6909 Triido-Thyronine,Sigma-Aldrich,T5516 "CTS-Vitronectin, truncated recombinant human (rhVTN−N)",Thermo Fisher Scientific,CTS279S3 IGF-1,Thermo Scientific,PHG0078 Rock Inhibitor (Y27632),Tocris,1254 SB431542,Tocris,1614 LDN193189,Tocris,6053 Cyclosporine A,AbbVie,NDC

(11) A continuous myofibroblast precursor cell line from the tail muscle of Australasian snapper (Chrysophrys auratus) that responds to transforming growth factor beta and fibroblast growth factorIn Vitro Cellular & Developmental Biology - AnimalDecember 1, 2022Gavril L. W. Chong, Björn Böhmert, Lucy E. J. Lee, Niels C. Bols, Georgina C. DowdNo. PHG9204, Thermo Fisher), insulin-like growth factor-1 (IGF-I, human recombinant, Catalogue No. PHG0071, Thermo Fisher), and insulin-like growth factor-2 (IGF-II, human recombinant, Catalogue No. PHG0084,

(12) GIGYF1 disruption associates with autism and impaired IGF-1R signalingJournal of Clinical InvestigationOctober 3, 2022Guodong Chen, Bin Yu, Senwei Tan, Jieqiong Tan, Xiangbin Jia, Qiumeng Zhang, Xiaolei Zhang, Qian Jiang, Yue Hua, Yaoling Han, et al.Western blot assay. GIGYF1 KO HEK293T cells and control HEK293T cells were stimulated with 200 μg/mL IGF1 (PHG0078, Thermo Fisher Scientific) at different times (0, 2, 5, 7, 10, or 30 minutes) and were lysed at 48 hours

(13) Pharmacologic Targeting of TFIIH Suppresses KRAS-Mutant Pancreatic Ductal Adenocarcinoma and Synergizes with TRAILCancer researchSeptember 16, 2022Moser R, Annis J, Nikolova O, Whatcott C, Gurley K, Mendez E, Moran-Jones K, Dorrell C, Sears RC, Kuo C, et al.supplement (354351-Corning): insulin (5μg/ml), transferrin (5μg/ml), selenium (5ng/ml), IGF-I (10ng/ml) (PHG0071-ThermoFisher Scientific), IGF-II (10ng/ml) (PHG0084 ThermoFisher Scientific), 10% fetal bovine serum

(14) Cellular senescence in hepatocytes contributes to metabolic disturbances in NASHFront Endocrinol (Lausanne)August 22, 2022Laurianne Bonnet, Ida Alexandersson, Ritesh K. Baboota, Tobias Kroon, Jan Oscarsson, Ulf Smith, Jeremie Boucherhuman recombinant insulin (Actrapid Penfill; Novo Nordisk, Bagsvard, Denmark) or IGF1 (Thermo Fisher, PHG0078) for 10 min. Cells were then washed once with PBS and lysed in lysis buffer for Western blot analysis.

(15) Early Dietary Exposures Epigenetically Program Mammary Cancer Susceptibility through Igf1-Mediated Expansion of the Mammary Stem Cell CompartmentCellsAugust 17, 2022Zheng Y, Luo L, Lambertz IU, Conti CJ, Fuchs-Young R.are described in the Supplemental Materials and Methods. Recombinant Igf1 (Life Technologies, cat# PHG0071, Waltham, MA, USA) and picropodophyllin (PPP, Santa Cruz, cat# sc-204008, Santa Cruz, CA, USA) were

(16) Studies of IGF-I and Klotho Protein in Relation to Anabolic-Androgenic Steroid and Growth Hormone AdministrationsFrontiers in Sports and Active LivingMarch 31, 2022Mikael Lehtihet, Christina Stephanou, Annica Börjesson, Hasanuzzaman Bhuiyan, Anton Pohanka, Lena Ekströmwas prepared by spiking the same serum with recombinant human IGF-I obtained from Invitrogen, ref: PHG0071, which gives concentration >500 ng/m. A sample volume of 50 μl was applied to the antibody-coated tubes.

(17) Genome-wide identification of the genetic basis of amyotrophic lateral sclerosisNeuronMarch 16, 2022Zhang S, Cooper-Knock J, Weimer AK, Shi M, Moll T, Marshall JNG, Harvey C, Nezhad HG, Franklin J, Souza CDS, et al.,ThermoFisher Scientific,#62249 All-trans retinoic acid,Sigma,#R2625 BDNF,PeproTech,#450-02 IGF,ThermoFisher Scientific,#PHG0078 CNTF,ThermoFisher Scientific,#PHC7015 N-2 supplement,ThermoFisher Scientific,#17502048 B-27 supplement,ThermoFisher Scientific

(18) Development of human alveolar epithelial cell models to study distal lung biology and diseaseiScienceFebruary 18, 2022Tran E, Shi T, Li X, Chowdhury AY, Jiang D, Liu Y, Wang H, Yan C, Wallace WD, Lu R, et al.(Enzo Life Sciences ALX-270-416), 6.7 ng/mL T3 (Sigma-Aldrich T6397), 1 μg/mL human IGF-1 (ThermoFisher PHG0078), 1 μg/mL human IL-6 (ThermoFisher PHC0064)], Jacob “progenitor specification” medium [Advanced DMEM/F12,

(19) Isolation and Propagation of Human Corneal Stromal Keratocytes for Tissue Engineering and Cell TherapyCellsJanuary 5, 2022Nur Zahirah binte M. Yusoff, Andri K. Riau, Gary H. F. Yam, Nuur Shahinda Humaira binte Halim, Jodhbir S. MehtaGermany, cat. no. 130-104-169);(17)Recombinant human insulin-like growth factor 1 (IGF-1; Gibco, cat. no. PHG0078);(18)L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate (Sigma-Aldrich, cat. no. A8960);(19)Fetal

(20) SNORD116 and growth hormone therapy impact IGFBP7 in Prader–Willi syndromeGenetics in MedicineSeptember 1, 2021Sanaa Eddiry et al.difference. Reagents Unless otherwise specified, all reagents used were Sigma-Aldrich products. IGF1 (PHG0078) was from Thermo-Fisher Scientific (Waltham, MA, USA). RESULTS Elevated IGFBP7 plasma level observed

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Human IGF-I Recombinant Protein from Thermo Fisher Scientific

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Human IGF-I Recombinant Protein from Thermo Fisher Scientific

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