Human IL-1 beta Recombinant Protein RIL1BI from Thermo Fisher Scientific

Product Specs
ItemHuman IL-1 beta Recombinant Protein
CompanyThermo Fisher Scientific
Price Supplier Page View Company Product Page
Catalog NumberRIL1BI
ApplicationsCELL CULTURE
Size20 µg
Regulatory StatusFor Research Use Only. Not for use in diagnostic procedures

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Thermo Fisher Scientific

168 Third Avenue

Waltham, MA 02451

United States

Phone: 800-678-5599

Company Profile

Website: www.thermofisher.com

(1) ACE‐mediated Glycosylation Stabilizes PSAP To Promote GPR37‐dependent Macrophage‐Nucleus Pulposus Cells Crosstalk and TGFβ Signaling in Alleviating Intervertebral Disc DegenerationAdvanced ScienceNovember 1, 2025Youfeng Guo, Feng Wang, Bijun Wang, Yu Zhou, Chao Wang, Tao Hu, Desheng WuTreatments and Transfection For in vitro IDD modeling, NP cells were treated with 10 ng mL−1 IL‐1β (RIL1BI, Thermo Fisher) or 10 ng mL−1 TNF‐α (HY‐P70800, MedChemExpress) for 72 h. Various treatments were applied

(2) Tie2-mediated CBL ubiquitination of EGFR underlies ultrasound-responsive silk fibroin/graphene oxide hydrogel-troxerutin therapy for intervertebral disc degenerationMaterials Today BioOctober 1, 2025Youfeng Guo, Xiao Liu, Chao Wang, Shuguang Wang, Yufeng Huang, Shuo Ding, Zeyu Wang, Feng Wanginvestigations involved treating NP cells with interleukin-1β (IL-1β) at a concentration of 10 ng/mL (RIL1BI, Thermo Fisher), Trox at 10 μM (HY-N0139, MedChemExpress), or HY-143404 at 10 μM (MedChemExpress). The

(3) Exploring Negative Feedback Mechanisms in the PTEN-ACE Axis: Application of Electrosorb Hydrogel-Based Gene Delivery for Intervertebral Disc RegenerationInternational Journal of Biological SciencesMay 15, 2025Youfeng Guo, Feng Wang, Yu Zhou, Bijun Wang, Chao Wang, Tao Hu, Desheng Wuwere treated with various drugs at the following concentrations: interleukin-1β (IL-1β) (10 ng/mL, RIL1BI; Thermo Fisher, Waltham, MA, USA), Thiamet-G (TMG) (10 μM, HY-12588; MedChemExpress, Monmouth Junction,

(4) Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neuronsCell Stem CellMay 2, 2024Osama Al-Dalahmah, Matti Lam, Julie J. McInvale, Wenhui Qu, Trang Nguyen, Jeong-Yeon Mun, Sam Kwon, Nkechime Ifediora, Aayushi Mahajan, Nelson Humala, et al.BDNF,Peptrotech,Cat#450–02-10uG Ascorbic Acid,Sigma,Cat#A4544–100G Recombinant Human IL-1β,ThermoFisher,Cat#RIL1BI Recombinant Human IL-34 Protein,R&D Systems,Cat#5265-IL-010/CF Insulin-Transferrin-Selenium,ThermoFisher,Cat#41400045 MEM

(5) Remifentanil does not affect human microglial immune activation in response to pro-inflammatory cytokinesEXCLI JFebruary 24, 2023Cinzia Dello Russo, Natalia Cappoli, Elisabetta Tabolacci, Liliana Sollazzi, Pierluigi Navarra, Paola Acetorecombinant pro-inflammatory cytokines, namely the human TNFα (cat. n. RTNFAI) and the human IL-1β (cat. n. RIL1BI) were from Invitrogen (Thermo Fisher Scientific). The human interferon-γ (IFNγ, cat. n. SRP3058) was

(6) Assessing human iPSC-derived microglia identity and function by immunostaining, phagocytosis, calcium activity, and inflammation assaySTAR protocolsDecember 16, 2022Hübschmann V, Korkut-Demirbaş M, Siegert S.,Thermo Scientific,Cat#21083027 Human IFNy,Sigma-Aldrich,Cat#SRP3058-100UG Human IL1β,Thermo Scientific,Cat#RIL1BI Lipopolysaccharid (LPS),Sigma-Aldrich,Cat#L5886-10MG Human M-CSF,PeproTech,Cat#300-25 MEM Non-essential Amino Acid Solution (100

(7) IFNγ-dependent silencing of TFF1 during Helicobacter pylori infectionOpen biologyDecember 1, 2022Eletto D, Mentucci F, Vllahu M, Voli A, Petrella A, Boccellato F, Meyer TF, Porta A, Tosco A.BMS303, Austria), 40 ng ml−1 TNFα (Invitrogen, no. BMS301, Austria) and 40 ng ml−1 IL1β (Invitrogen, no. RIL1BI, USA) for 24 h alone or in combination. Mucosoids were cultured for two weeks, infected with H. pylori

(8) A systematic characterization of microglia-like cell occurrence during retinal organoid differentiationiScienceJuly 15, 2022Bartalska K, Hübschmann V, Korkut-Demirbaş M, Cubero RJA, Venturino A, Rössler K, Czech T, Siegert S.were treated with human IFN-γ (Sigma-Aldrich, Cat#SRP3058-100UG) and IL1-β (Thermo Scientific, Cat#RIL1BI) or both with a final concentration of 10ng/mL of each cytokine per well, with LPS (Sigma-Aldrich, Cat#L5886-10MG)

(9) Signature for Pain Recovery IN Teens (SPRINT): protocol for a multisite prospective signature study in chronic musculoskeletal painBMJ OpenJune 8, 2022Laura Simons et al.containing 1 µg lipopolysaccharide (Invivogen TLRLPEKLPS), 1 µg recombinant human interleukin-1β (Invitrogen RIL1BI), a cocktail of 100 ng each recombinant human interleukin-2 (Peprotech 200–02), interleukin-4 (Peprotech

(10) Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal AdenocarcinomaCancersDecember 17, 2020Holokai L, Chakrabarti J, Lundy J, Croagh D, Adhikary P, Richards SS, Woodson C, Steele N, Kuester R, Scott A, et al.consisting of human dendritic cell medium supplemented with 10 ng/mL IL-1β (Thermo Fisher Scientific, RIL1BI), 10 ng/mL 1L-6 (Thermo Fisher Scientific, RIL6I), 1 μg/mL PGE2 (TOCRIS, 2296) and 10 ng/mL TNF-α (Thermo Fisher Scientific

(11) Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8⁺ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer ImmunotherapyImmunityOctober 13, 2020Weulersse M, Asrir A, Pichler AC, Lemaitre L, Braun M, Carrié N, Joubert MV, Le Moine M, Do Souto L, Gaud G, et al.300-03 Recombinant human IL-4 Pepro Tech Cat#: 200-04 Recombinant human IL-1b Thermo Fisher Scientific Cat#:RIL1BI Recombinant human TNF-a Thermo Fisher Scientific Cat#: RTNFAI Recombinant human IL-15 R&D Systems Cat#:

(12) The mTOR kinase inhibitor rapamycin enhances the expression and release of pro-inflammatory cytokine interleukin 6 modulating the activation of human microglial cellsEXCLI journalJanuary 1, 2019Cappoli N, Mezzogori D, Tabolacci E, Coletta I, Navarra P, Pani G, Dello Russo C.the human tumor necrosis factor α (TNFα, cat. n. RTNFAI) and the human interleukin-1β (IL-1β, cat. n. RIL1BI) were from Invitrogen (Thermo Fisher Scientific) and are produced in yeast. The lyophilized TNFα was

(13) A 3D cartilage - inflammatory cell culture system for the modeling of human osteoarthritisBiomaterialsAugust 1, 2011Sun L, Wang X, Kaplan DL.cytokines TNF-α (cat # 210-TA/CF, lot # AA3308062, R & D system, Minneapolis, MN) and IL-1β (Prod# RIL1BI, lot # JG125416, Pierce Biotech, Rockford, IL) were added to the culture medium directly. All supplements

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Human IL-1 beta Recombinant Protein from Thermo Fisher Scientific

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Human IL-1 beta Recombinant Protein from Thermo Fisher Scientific

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