Description
Recombinant human DPP4 (29-766) Protein was expressed in CHO cells using a C-terminal His tag.
Overview: The Middle East respiratory syndrome Corona virus (MERS-CoV) has caused the MERS outbreak that first originated in Saudi Arabia, but since has spread to other countries around the world (1). The spike glycoprotein (S) of Corona virus belongs to the type I transmembrane protein containing two subunits (2), S1 and S2, which is known to be the key component to bind with host cells through interaction with dipeptidyl peptidase 4 (DPP4) (3). MERS-CoV can recognize DPP4 through its receptor binding domain (RBD) of S1 to initiate viral infection in humans (2)