Recombinant Human Regulator of G-Protein Signaling 17 (RGS17) (Active) from MyBioSource.com

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Recombinant Human Regulator of G-Protein Signaling 17 (RGS17) (Active)

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Description

Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins