Description
Full-length recombinant human CAMK1gamma was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_020439.
CAMKIgamma (CLICK-III), a member of CAMK family, is a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase. Full activation of CaMKIgamma requires both Ca(2+)/CaM and phosphorylation by CAMKK. CAMKIgamma transcripts is most abundant in neurons, with the highest levels in limited nuclei such as the central nucleus of the amygdala (CeA) and the ventromedial hypothalamus (1)