AMPK (A2/B2/G1), Active MBS517432 from MyBioSource.com

Description

Recombinant full-length mouse AMPK (combination of A2/B2/G1 subunits) was expressed by baculovir us in Sf9 insect cells using a N-terminal His tag. The gene accession numbers for the three subunits (A2/B2/G1) are, NM_178143, NM_182997, and NM_016781.
AMP-activated protein kinase (AMPK) exhibits a key role as a master regulator of cellular energy homeostasis (1). AMPK exists as a heterotrimeric complex composed of a catalytic alpha subunit and regulatory beta and gamma subunits. Binding of AMP to the gamma subunit allosterically activates the complex. AMPK is activated in response to stresses that deplete cellular ATP (low glucose, hypoxia and ischemia)(2) and via signaling pathways in response to adiponectin, leptin and CAMKKbeta

Product Specs
ItemAMPK (A2/B2/G1), Active
CompanyMyBioSource.com
Price $485.00Supplier Page View Company Product Page
Catalog NumberMBS517432
FormatRecombinant protein stored in 50mM sodium phosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol
ApplicationsKinase Assay, Western Blot (WB)
Molecular Weight68~72kDa (A2), ~35kDa (B2), and ~40kDa (G1)
NCBI Full Gene Nameprotein kinase, AMP-activated, beta 2 non-catalytic subunit, protein kinase, AMP-activated, alpha 2 catalytic subunit, protein kinase, AMP-activated, gamma 1 non-catalytic subunit
NCBI Gene AliasesPr, AMPK, AA571379, A830082D05, AW049591, 2310008I11Rik, BB124140, BB036179, 5730553K21Rik, AMPKalpha2, Prkaac
Size0.005 mg
Molecule NameAMPK (A2/B2/G1)
TypeRecombinant Protein
Source/Expression SystemSf9 insect cells