Description
Recombinant EBV glycoprotein Hand gp42 proteins expressed andpurified from 293 cells. C-terminal 6xhis-tagged recombinant EBV gHprotein (amino acid 1-679) (GenBank accession#: P03231) and EBV gp42 (aa 31-223) (GenBank accession#: YP_401672) complex
Introduction: Herpesviruses have an envelope andan outer lipid bilayer which contains twelve surface glycoproteins. For infectivity to be attained, the double stranded DNA genome of EBV must enter the host cell through means of fusion of its envelope with the cellular membrane or via endocytosis. Epstein–Barr virus (EBV)can infect both B cells and epithelial cells. The mechanisms for entering these two cells are different. The viral three-part glycoprotein complexes of gHgL/gp42 mediate B cell membrane fusion