Description
Human epidermal growth factor (EGF, also known as beta-urogastrone) is a 53 amino acid peptide that regulates cell growth, proliferation, and differentiation. EGF is an integral membrane protein that is cleaved and released into the extracellular space where it acts as a hormone. EGF binds cell surface EGF receptors (EGFR), initiating signaling cascades through activation of EGFR tyrosine kinase activity