Description
Recombinant full-length rat BMX was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_001109016.
The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells (1). The BMX gene is located on chromosomal band Xp22.2 between the DXS197 and DXS207 loci. Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia. BMX is found to induce activation of the Stat signaling pathway (2)