Description
Recombinant full-length human PPP2R1A was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The PPP2R1A gene accession number is NM_014225.
PPP2R1A or the PR65 subunit of protein phosphatase 2A (PP2A) acts as a scaffolding protein to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit, together forming the core of heterodimeric PP2A. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis