Description
Recombinant human UBE2N (2-end) was expressed in E Coli cells using an N-terminal His tag. The UBE2N gene accession number is NM_003348.
UBE2N (UBC13) or ubiquitin-conjugating enzyme E2N is a member of the E2 ubiquitin-conjugating enzyme family which plays a role in DNA post-replication repair. UBE2N gene encodes a novel human E2 that may be involved in protein degradation in the muscles and testis. UBE2N plays a role in initiation of homologous recombination during double-strand break repair. UBE2N activity may have therapeutic uses in controlling inflammatory responses and it is also important in the induction of immune responses