Description
Recombinant human PTPRS (883-1210) was expressed in E Coli cells using an N-terminal GST tag. The gene accession number is NM_130855.
PTPRS is a member of a subfamily of receptor type PTPases that is characterized by the presence of an extracellular cell adhesion molecule-like motif and 2 intracellular phosphatase domains (1). The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis (2)