Recombinant Mouse Nectin-4 (C-Fc) MBS2569306 from MyBioSource.com

Description

Nectin-4(PVRL4)isatypeItransmembraneglycoproteinwhichbelongstothenectinfamilyofIgsuperfamilyproteins.ItcontainstwoIg-likeC2-typedomainsandoneIg-likeV-typedomain.PVRL4seemstobeinvolvedincelladhesionthroughtrans-homophilicand-heterophilicinteractions,thelatterincludingspecificallyinteractionswithnectin-1.Itdoesnotactasreceptorforalpha-herpesvirusentryintocells.Itispredominantlyexpressedinplacenta,theembryoandbreastcarcinoma.Butitisnotdetectedinnormalbreastepithelium.Thesolubleformisproducedbyproteolyticcleavageatthecellsurface(shedding),probablybyADAM17.Mutationsinthisgenearethecauseofectodermaldysplasia-syndactylysyndrometype 1, an autosomal recessive disorder

Product Specs
ItemRecombinant Mouse Nectin-4 (C-Fc)
CompanyMyBioSource.com
Price $165.00Supplier Page View Company Product Page
Catalog NumberMBS2569306
Molecular Weight55,657 Da
Purity>95% as determined by reducing SDS-PAGE
NCBI Full Gene Namenectin cell adhesion molecule 4
NCBI Gene AliasesP, Prr4, Pvrl4, 1200017F15Rik
Size0.01 mg
Molecule NameNectin-4
Domain/Region/TerminusGly31-Ser349
Source/Expression SystemHuman Cells
FormatLyophilized from a 0.2um filtered solution of 20mM PB, 150mM NaCl, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual