Description
D-gluconate kinase or idnk is a thermosensitive protein, consists of 187 a. A and part of the gluconokinase gntK/gntV protein family. Idnk enhances the conversion of ATP + D-gluconate => ADP + 6-phospho-D-gluconate. Idnk has a crucial part in determination of gender, removal of a certain portion of 9p may result in the making of male to female (reversal of sex), that leads to a female that has the genotype of male X, Y.
IDNK Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids (1-187) and having a molecular mass of 23.4 kDa. IDNK is fused to a 23 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques