Description
Growth regulated protein alpha (GRO-α), also known as CXCL1, is a chemokine that has mitogenic properties and is a neutrophil chemoattractant. GRO- α is secreted by macrophages, epithelial cells, neutrophils, and melanomas. GRO- α signals through the CXCR2 chemokine receptor and is important during spinal cord formation, inflammation, angiogenesis, tumorigenesis, and wound healing