Human Nectin-2 Protein (Fc & AVI Tag), Biotinylated 10005-H41H-B from Sino Biological, Inc.

Product Specs
ItemHuman Nectin-2 Protein (Fc & AVI Tag), Biotinylated
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10005-H41H-B
TypeRecombinant protein
Molecule NameNECTIN2
Conjugate/TagC-human IgG1-Fc, AVI
Size20 µg
SpeciesHuman
NCBI Full Gene Namenectin cell adhesion molecule 2
NCBI Gene AliasesCD112, HVEB, PRR2, PVRL2, PVRR2
FormatLyophilized from sterile PBS, pH 7.4
Source/Expression SystemHEK293 Cells
Molecular WeightThe recombinant human NECTIN2 consists of 582 amino acids and predicts a molecular mass of 64.08 kDa. It migrates as an approximately 75.99 kDa band in SDS-PAGE under reducing conditions
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
Activity1.Measured by its binding ability in a functional ELISA. Immobilized Human PVRIG hFc(Cat:28312-H02H2) at 2 µg/mL (100 µL/well) can bind Human Nectin-2 (ECD, hFc & AVI Tag), Biotinylated(Cat:10005-H41H-B), the EC50 of Human Nectin-2 (ECD, hFc & AVI Tag), Biotinylated(Cat:10005-H41H-B) is 10-60 ng/mL(QC tested). 2.Serial dilutions of anti-TIGIT (Research Grade Tiragolumab biosimilar) were added into Recombinant Human TIGIT / VSTM3 Protein (His Tag) (Cat: 10917-H08H3): Recombinant Human CD155 / PVR Protein (ECD, Fc & AVI Tag), Biotinylated (Cat: 10109-H41H-B) binding reactions. The half maximal inhibitory concentration (IC50) is 1014.8 ng/mL (Routinely tested)