Description
CXCL9 belongs to the CXC chemokine family and also known as Monokine induced by gamma interferon (MIG). It is a T-cell chemoattractant induced by IFN-γ. CXCL9 is closely related to two other CXC chemokines called CXCL10 and CXCL11, additionally they all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3. It is a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response and chemotactic for activated T-cells. Recombinant Mouse CXCL9 contains 105 amino acids which is a single non-glycosylated polypeptide chain. Furthermore, The Mouse CXCL9 shares 75 % and 88 % a.a. sequence identity with human and rat CXCL9