Recombinant Mouse MCP-5/CCL12 protein CD00306 from Bioassay Technology Laboratory

Description

Mouse CCL12 is belonging to the CC chemokine family. It shows 66 % amino acid sequence identity to human MCP-1. CCL12 has been shown to be a potent chemoattractant for monocytes and lymphocytes but not neutrophils. At high concentrations, it will also chemoattract eosinophils. CCL12 can induce a calcium flux in human HEK-293 cells transfected with Mouse CCR2, but can not induce a calcium flux in HEK-293 cells transfected with CCR1, CCR3, or CCR5. That shows the functional receptor of CCL12 is CCR2

Product Specs
ItemRecombinant Mouse MCP-5/CCL12 protein
CompanyBioassay Technology Laboratory
Price $176.00Supplier Page View Company Product Page
Catalog NumberCD00306
Size5 ug
Molecular WeightApproximately 9.3 kDa, a single non-glycosylated polypeptide chain containing 82 amino acids
HostEscherichia coli
FormatLyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4
Research AreaImmunology
Purity> 95 % by SDS-PAGE and HPLC analyses
ActivityFully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 10-50 ng/ml
NCBI Full Gene Namechemokine (C-C motif) ligand 12
NCBI Gene AliasesMCP-, MCP-5, Scya, Scya12