Recombinant Human EPO Alpha-Fc protein CD01853 from Bioassay Technology Laboratory

Description

Erythropoietin (EPO), a glycoprotein produced primarily by the kidney, is the principal factor that regulates erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells. The production of EPO by kidney cells is increased in response to hypoxia or anemia. Recombinant EPO has been approved for the treatment of anemia associated with chronic renal failure as well as for anemia of AZT treated AIDS patients

Product Specs
ItemRecombinant Human EPO Alpha-Fc protein
CompanyBioassay Technology Laboratory
Price $282.00Supplier Page View Company Product Page
Catalog NumberCD01853
Size2 ug
Molecular WeightRecombinant Human EPO/Fc produced in CHO is a dimeric, glycosylated, polypeptide chain consisting of two mature human EPO molecules linked to the Fc portion of human IgG1. The Fc component contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. As a result of glycosylation, the recombinant protein migrates with an apparent molecular mass of 140 kDa in non-reducing SDS-PAGE
HostCHO
FormatLyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4
Research AreaImmunology
Purity> 98 % by SDS-PAGE and HPLC analyses
ActivityFully biologically active when compared to standard. The Specific Activity was measured by the stimulation of reticulocyte production in normocyth-aemic mice and is no less than 5.0 × 105 IU/mg
NCBI Full Gene Nameerythropoietin
NCBI Gene AliasesDBAL, ECYT5, EP, MVCD2