Recombinant Human MIP-4/CCL18 protein CD01278 from Bioassay Technology Laboratory

Description

Human CCL18 is encoded by the CCL18 gene located on the chromosome 17. As also named MIP-4, it shares 61 % sequence identity to human MIP-1α. CCL18 is mainly expressed by lung and some lymphoid tissues like lymph nodes express CCL18 at low level. It is chemotactic for both activated (CD3+) T cells and nonactivated (CD14-) lymphocytes, but not for monocytes or granulocytes. Involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 plays a role in both humoral and cell-mediated immunity responses

Product Specs
ItemRecombinant Human MIP-4/CCL18 protein
CompanyBioassay Technology Laboratory
Price $409.00Supplier Page View Company Product Page
Catalog NumberCD01278
Size2 ug, 10 ug
Molecular WeightApproximately 7.9 kDa, a single non-glycosylated polypeptide chain containing 69 amino acids
HostEscherichia coli
FormatLyophilized from a 0.2 µm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl
Research AreaImmunology
Purity> 97 % by SDS-PAGE and HPLC analyses
ActivityFully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 1.0-10 ng/ml
NCBI Full Gene NameC-C motif chemokine ligand 18
NCBI Gene AliasesAMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18