Human MST1 Baculovirus-Insect cells Overexpression Lysate MBS8114565 from MyBioSource.com

Description

Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially regulates TLR3/4/9-mediated inflammatory responses in macrophages and thereby is protective against chronic inflammation-associated Hepatocellular carcinoma (HCC). STK4 has potential as a biomarker and therapeutic target for inflammation-induced HCC.

This Human MST1 overexpression lysate was created in Baculovirus-Insect cells and intented for use as a Western blot (WB) positive control. Purification of MST1 protein from the overexpression lysate was verified

Product Specs
ItemHuman MST1 Baculovirus-Insect cells Overexpression Lysate
CompanyMyBioSource.com
Price $260.00Supplier Page View Company Product Page
Catalog NumberMBS8114565
Format1x Sample Buffer (1x modified RIPA buffer+1x SDS loading buffer).
Modified RIPA Lysis Buffer: 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 1mM EDTA, 1% Triton X-100, 0.1% SDS, 1% Sodium deoxycholate, 1mM PMSF
ApplicationsWestern Blot (WB)
Size0.3 mg
Molecular Weight52,335 Da
NCBI Full Gene Nameserine/threonine kinase 4
NCBI Gene AliasesKRS2, MST1, YSK3
Molecule NameMST1
TypeOverexpression Lysate
Domain/Region/TerminusGlu2-Phe487
Source/Expression SystemBaculovirus-Insect cells