Human RNF43 HEK293 Overexpression Lysate MBS8115654 from MyBioSource.com

Description

RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expressed oncogenes in malignant colorectal tumors. RNF43 is a tumour suppressor gene that suppresses the Wnt-beta-catenin signalling pathway.

This Human RNF43 overexpression lysate was created in HEK293 Cells and intented for use as a Western blot (WB) positive control. Purification of RNF43 protein from the overexpression lysate was verified

Product Specs
ItemHuman RNF43 HEK293 Overexpression Lysate
CompanyMyBioSource.com
Price $260.00Supplier Page View Company Product Page
Catalog NumberMBS8115654
Format1x Sample Buffer (1x modified RIPA buffer+1x SDS loading buffer).
Modified RIPA Lysis Buffer: 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 1mM EDTA, 1% Triton X-100, 0.1% SDS, 1% Sodium deoxycholate, 1mM PMSF
ApplicationsWestern Blot (WB)
Size0.3 mg
Molecular Weight85,722 Da
NCBI Full Gene Namering finger protein 43
NCBI Gene AliasesRNF124, URCC, SSPCS
Molecule NameRNF43
TypeOverexpression Lysate
Domain/Region/TerminusMet1-Tyr197
Source/Expression SystemHEK293 Cells
Cell LineHEK293