Human PARP3 Baculovirus-Insect cells Overexpression Lysate MBS8114464 from MyBioSource.com

Description

Poly(ADP-ribose) polymerase 3 (PARP3) is an important member of the PARP family and shares high structural similarities with both PARP1 and PARP2. Poly(ADP-ribose) polymerase 3 (PARP3), a critical player in cellular response to DNA double-strand breaks (DSBs), plays an essential role in the maintenance of genome integrity. The ADP ribosyl transferase [poly(ADP-ribose) polymerase] ARTD3(PARP3) is a newly characterized member of the ARTD(PARP) family that catalyzes the reaction of ADP ribosylation, a key posttranslational modification of proteins involved in different signaling pathways from DNA damage to energy metabolism and organismal memory.

This Human PARP3 overexpression lysate was created in Baculovirus-Insect cells and intented for use as a Western blot (WB) positive control. Purification of PARP3 protein from the overexpression lysate was verified

Product Specs
ItemHuman PARP3 Baculovirus-Insect cells Overexpression Lysate
CompanyMyBioSource.com
Price $260.00Supplier Page View Company Product Page
Catalog NumberMBS8114464
Format1x Sample Buffer (1x modified RIPA buffer+1x SDS loading buffer).
Modified RIPA Lysis Buffer: 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 1mM EDTA, 1% Triton X-100, 0.1% SDS, 1% Sodium deoxycholate, 1mM PMSF
ApplicationsWestern Blot (WB)
Size0.3 mg
Molecular Weight60,070 Da
NCBI Full Gene Namepoly(ADP-ribose) polymerase family member 3
NCBI Gene AliasesARTD3, PADPRT-3, IRT1, ADPRTL2, ADPRTL3, ADPRT3
Molecule NamePARP3
TypeOverexpression Lysate
Domain/Region/TerminusMet1-Leu533
Source/Expression SystemBaculovirus-Insect cells