Description
Product Characteristics: Extracellular Domain Protein
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Target Information: This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules\, however, it does not associate with beta-2-microglobulin or bind peptides. [provided by RefSeq, Jul 2008]