Prostaglandin E2-d4 314010 from Cayman Chemical

Product Specs
ItemProstaglandin E2-d4
CompanyCayman Chemical
Price $76.00Supplier Page View Company Product Page
Catalog Number314010
FormatA 500 µg/ml solution in methyl acetate
Research AreaCyclooxygenase Pathway, Immunology & Inflammation, Inflammatory Lipid Mediators, Lipid Biochemistry, Prostaglandins
Molecular Weight356.5
Size50 µg
Purity≥99% deuterated forms (d1-d4)
Storage-20
FormulaC20H28D4O5
OriginUSA

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) 12-Hydroxyheptadecatrienoic Acid Predicts Hepatocellular Carcinoma Development During Nucleos(t)ide Analogue TherapyCancers (Basel)February 7, 2026Hiroko Ikenaga, Ritsuzo Kozuka, Kirara Inoue, Tsutomu Matsubara, Naoshi Odagiri, Kanako Yoshida, Kohei Kotani, Etsushi Kawamura, Atsushi Hagihara, Hideki Fujii, et al.internal standard mixture of 10 ng/mL prostaglandin (PG) E2-d4 (Cayman Chemical, Ann Arbor, MI, USA; 314010), 10 ng/mL leukotriene (LT) B4-d4 (Cayman Chemical; 320110), and 100 ng/mL arachidonic acid (AA)-d8

(2) IL-13 decreases susceptibility to airway epithelial SARS-CoV-2 infection but increases disease severity in vivo via eicosanoid signallingeBioMedicineOctober 1, 2025Shreya Ghimire, Biyun Xue, Kun Li, Ryan M. Gannon, Christine L. Wohlford-Lenane, Andrew L. Thurman, Huiyu Gong, Grace C. Necker, Jian Zheng, David K. Meyerholz, et al.(10009799) and 15d-PGJ2 (18570), matched internal standards were AA-d8 (390010), PGD2-d4 (312010), PGE2-d4 (314010), 6-keto-PGF1α-d4 (315210), PGF2α-d4 (316010), LTB4-d4 (320110), TXB2-d4 (319030), 15(S)-HEPE-d5 (31221),

(3) ATP Alters the Oxylipin Profiles in Astrocytes: Modulation by High Glucose and MetforminBrain SciMarch 11, 2025Alexey I. Drozhdev, Vladislav O. Gorbatenko, Sergey V. Goriainov, Dmitry V. Chistyakov, Marina G. Sergeevaoxylipins standards were 6-keto PGF1α-d4 (#315210), TXB2-d4 (#319030), PGF2α-d4 (#316010), PGE2-d4 (#314010), PGD2-d4 (#312010), 5(S)-HETE-d8 (#334230), 12(S)-HETE-d8 (#334570), 15(S)-HETE-d8 (#334720), EPA-d5

(4) Crosstalk Between nNOS/NO and COX-2 Enhances Interferon-Gamma-Stimulated Melanoma ProgressionCancers (Basel)January 31, 2025Anika Patel, Shirley Tong, Moom R. Roosan, Basir Syed, Amardeep Awasthi, Richard B. Silverman, Sun Yangobtained from Santa Cruz Biotechnology (#sc-201225C, Dallas, TX, USA) and Cayman Chemical Company (#314010, Ann Arbor, MI, USA), respectively. 2.2. Reverse Phase Protein Array and the Cancer Proteome Atlas

(5) Roles of lipocalin-type and hematopoietic prostaglandin D synthases in mouse retinal angiogenesisJournal of Lipid ResearchOctober 1, 2023Daiki Horikami, Erika Sekihachi, Keisuke Omori, Yui Kobayashi, Koji Kobayashi, Nanae Nagata, Kaori Kurata, Akiyoshi Uemura, Takahisa Murataμl DW. After the centrifugation, 800 μl of supernatants were added with internal standards, PGE2-d4 (314010; Cayman chemical, MA) and PGD2-d4 (312010; Cayman chemical) and then purified by solid phase extraction

(6) Multiplexed targeted analysis of polyunsaturated fatty acids and oxylipins using liquid chromatography-tandem mass spectrometrySTAR ProtocolsSeptember 1, 2023Evgenia Turtoi, Jeremy Jeudy, Gilles Valette, Christine Enjalbal, Isabelle K. Vila, Nadine Laguette, Andrei TurtoiLeukotriene B4-d4,Cayman,320110 Oleoyl ethanolamide-d4,Cayman,9000552 PAF C-16-d4,Cayman,360900 Prostaglandin E2-d4,Cayman,314010 Thromboxane B2-d4,Cayman,319030 CELL CULTURE,CELL CULTURE,CELL CULTURE DMEM,Thermo Fisher,10566016 0.25%

(7) A multi-omics based anti-inflammatory immune signature characterizes long COVID-19 syndromeiScienceJanuary 20, 2023Johannes J. Kovarik, Andrea Bileck, Gerhard Hagn, Samuel M. Meier-Menches, Tobias Frey, Anna Kaempf, Marlene Hollenstein, Tarik Shoumariyeh, Lukas Skos, Birgit Reiter, et al.cell culture",Sigma-Aldrich,L6529-1MG 12S-HETE-d8,Cayman,334570 15S-HETE-d8,Cayman,334230 5-Oxo-ETE-d7,Cayman,334250 "11,12-DiHETrE-d11",Cayman,10007975 PGE2-d4,Cayman,314010 20-HETE-d6,Cayman,390030 ,, Critical commercial assays,Critical commercial assays,Critical commercial

(8) Sebocytes contribute to melasma onsetiScienceMarch 18, 2022Flori E, Mastrofrancesco A, Mosca S, Ottaviani M, Briganti S, Cardinali G, Filoni A, Cameli N, Zaccarini M, Zouboulis CC, et al.(Z)-3,3,4,4-tetradeuterio-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid) (purity ≥99%)",Cayman Chemical,Cat#314010 "Prostaglandin F2α (IUPAC Name: (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic

(9) Signaling Lipidomic Analysis of Thermogenic AdipocytesMethods in Molecular BiologyFebruary 24, 2022Sean D. Kodani, Valerie Bussberg, Niven R. Narain, Michael A. Kiebish, Yu-Hua Tsengd8-5(S)-HETE (Cayman Chemical, 334230) d4-LTB4 (Cayman Chemical, 320110) d4-PGE2 (Cayman Chemical, 314010) 12,13-diHOME (Cayman Chemical, 10009832) 12-HEPE (Cayman Chemical, 32540) 500 mg/6 mL ISOLUTE

(10) Pulmonary infection induces persistent, pathogen-specific lipidomic changes influencing trained immunityiScienceSeptember 24, 2021Roberts LM, Schwarz B, Speranza E, Leighton I, Wehrly T, Best S, Bosio CM.11184 D5-LXA4,Cayman Chemical,Cat #: 24936 D4-LTB4,Cayman Chemical,Cat #: 29629 D4-PGE2,Cayman Chemical,Cat #: 314010 RvE1,Cayman Chemical,Cat #: 10007848 LXA4,Cayman Chemical,Cat #: 90410 LXA5,Cayman Chemical,Cat #:

(11) Global profiling of gut microbiota-associated lipid metabolites in antibiotic-treated mice by LC-MS/MS-based analysesSTAR ProtocolsJune 1, 2021Nobuyuki Okahashi, Masahiro Ueda, Shu Yasuda, Hiroshi Tsugawa, Makoto Aritawater (18 MΩ),Merck,n/a Acetic acid LC-MS CHROMASOLV,FLUKA,49199-50ML-F Prostaglandin E2-d4,Cayman,314010 Leukotriene B4-d4,Cayman,320110 Leukotriene D4-d5,Cayman,10006199 15-Hydroxyeicosatetraenoic acid-d8,Cayman,334720 Arachidonic acid-d8

(12) Pro-resolving lipid mediator lipoxin A₄ attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidomeCell reportsJune 1, 2021Derada Troletti C, Enzmann G, Chiurchiù V, Kamermans A, Tietz SM, Norris PC, Jahromi NH, Leuti A, van der Pol SMA, Schouten M, et al.334230 d4-LTB4,Cayman Chemical,Cat# 320110 d5-LXA4,Cayman Chemical,Cat# 10007737 d4-PGE2,Cayman Chemical,Cat# 314010 d5-RvD2,Cayman Chemical,Cat# 11184 C18 columns,Thermo Fisher,Cat# SI928975–906 Methyl formate,Sigma

(13) Linoleic acid-derived 13-hydroxyoctadecadienoic acid is absorbed and incorporated into rat tissuesBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsMarch 1, 2021Zhichao Zhang, Shiva Emami, Marie Hennebelle, Rhianna K. Morgan, Larry A. Lerno, Carolyn M. Slupsky, Pamela J. Lein, Ameer Y. Tahad4–9-HODE (Cat No. 338410, Cayman Chemical), d4-LTB4 (Cat No. 320110, Cayman Chemical), d4-PGE2 (Cat No. 314010, Cayman Chemical), d4-TXB2 (Cat No. 319030, Cayman Chemical), d6–20-HETE (Cat No. 390030, Cayman Chemical)

(14) Comparison of PPAR Ligands as Modulators of Resolution of Inflammation, via Their Influence on Cytokines and Oxylipins Release in AstrocytesInternational Journal of Molecular SciencesDecember 16, 2020Dmitry V. Chistyakov, Alina A. Astakhova, Sergei V. Goriainov, Marina G. Sergeeva6-keto PGF1α-d4 (cat.no. 315210), TXB2-d4 (cat.no. 319030), PGF2α-d4 (cat.no. 316010), PGE2-d4 (cat.no. 314010), PGD2-d4 (cat.no. 312010), 5(S)-HETE-d8 (cat.no. 334230), 12(S)-HETE-d8 (cat.no. 334570), 15(S)-HETE-d8

(15) Impairment of spatial memory accuracy improved by Cbr1 copy number resumption and GABAB receptor-dependent enhancement of synaptic inhibition in Down syndrome model miceScientific ReportsDecember 1, 2020Fumiko Arima-Yoshida et al.transferred to ice-cold methanol containing prostaglandin E2 and F2a standards (ratio 7:1:1, PGE2-d4 #314010 and PGF2a-d4 #316010: Cayman Chemical, Ann Arbor, MI, USA). Samples were homogenized by sonication and

(16) Inhibitor of Hyaluronic Acid Synthesis 4-Methylumbelliferone as an Anti-Inflammatory Modulator of LPS-Mediated Astrocyte ResponsesInternational journal of molecular sciencesNovember 2, 2020Chistyakov DV, Nikolskaya AI, Goriainov SV, Astakhova AA, Sergeeva MG.follows: 6-keto PGF1α-d4 (cat.no. 315210), TXB2-d4 (cat.no. 319030), PGF2α-d4 (cat.no. 316010), PGE2-d4 (cat.no. 314010), PGD2-d4 (cat.no. 312010), 5(S)-HETE-d8 (cat.no. 334230), 12(S)-HETE-d8 (cat.no. 334570), 15(S)-HETE-d8

(17) Distribution of Free and Esterified Oxylipins in Cream, Cell, and Skim Fractions of Human MilkLipidsNovember 1, 2020Junai Gan, Zhichao Zhang, Karina Kurudimov, J. Bruce German, Ameer Y. Tahad4-9-HODE (Cayman Chemical, Cat # 338410), d4-LTB4 (Cayman Chemical, Cat # 320110), d4-PGE2 (Cayman Chemical, Cat # 314010), d4-TXB2 (Cayman Chemical, Cat # 319030), d6-20-HETE (Cayman Chemical, Cat # 390030) and d8-5-HETE

(18) Paracrine orchestration of intestinal tumorigenesis by a mesenchymal nicheNatureApril 1, 2020Roulis M, Kaklamanos A, Schernthanner M, Bielecki P, Zhao J, Kaffe E, Frommelt LS, Qu R, Knapp MS, Henriques A, et al.homogenized in 500 μl PBS spiked with 100 μM butylated hydroxytoluene on ice. PGE2-d4 (Cayman, no. 314010) and PGD2-d4 (Cayman, no. 312010) were used as internal controls in each sample from the beginning of

(19) Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVSCellDecember 12, 2019Chao CC, Gutiérrez-Vázquez C, Rothhammer V, Mayo L, Wheeler MA, Tjon EC, Zandee SEJ, Blain M, de Lima KA, Takenaka MC, et al.analysis of lipid metabolites, samples were prepared by adding 90 μL of methanol containing PGE2-d4 (#314010, Cayman Chemical) as an internal standard to cell extract for lipid metabolites profile (30 μL) and

(20) Inhibitors of Oxidative Phosphorylation Modulate Astrocyte Inflammatory Responses through AMPK-Dependent Ptgs2 mRNA StabilizationCellsOctober 1, 2019Astakhova A, Chistyakov D, Thomas D, Geisslinger G, Brüne B, Sergeeva M, Namgaladze D.(6-keto PGF1α-d4 (cat.no. 315210), TXB2-d4 (cat.no. 319030), PGF2α-d4 (cat.no. 316010), PGE2-d4 (cat.no. 314010), PGD2-d4 (cat.no. 312010), LTB4-d4 (cat.no. 320110), 12(S)-HETE-d8 (cat.no. 334570) (Cayman Chemical,

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Prostaglandin E2-d4

Prostaglandin E2-d4

Prostaglandin E2-d4 from Cayman Chemical

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Cayman Chemical

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Prostaglandin E2-d4 from Cayman Chemical

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