Description
A neuropeptide and GAL receptor agonist; inhibits forskolin-induced cAMP production in HEK293E cells expressing recombinant human GAL1 receptors (EC50 = 0.031 nM) and stimulates inositol phosphate accumulation in CHO cells expressing recombinant human GAL2 receptors (EC50 = 12.3 nM); induces contractions in isolated rat longitudinal fundus strips (EC50 = 13.8 nM); reduces paw licking and flinching in the second phase of the formalin test in rats at 3, 10, and 30 nmol/animal intrathecally